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Clinical Trial Summary

The risk of colorectal cancer (CRC) is increased in patients having ulcerative colitis (UC). Patients with long-standing extensive colitis, concomitant primary sclerosing cholangitis, or previous history of dysplasia carry an exceptionally high risk of CRC and require regular and short-interval surveillance colonoscopy. Recent guidelines recommend surveillance colonoscopy based on target biopsy rather than random biopsy applying chromoendoscopy (CE) or narrow band image (NBI) technique in UC at risk for CRC. However, the diagnostic yield of NBI-based surveillance and CE-based surveillance is not extensively investigated in the high-risk UC population. The investigators aimed to compare the dysplasia detection rate of NBI with that of CE in UC patients with a high risk of CRC by performing a multicenter, randomized controlled trial.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04257084
Study type Interventional
Source Asan Medical Center
Contact Dong-Hoon Yang, MD, PhD
Phone 82-2-3010-5809
Email dhyang@amc.seoul.kr
Status Not yet recruiting
Phase N/A
Start date December 2020
Completion date January 2023

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