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Optimal Fecal Microbiota Transplant Dosing for Mild to Moderate Ulcerative Colitis

Ulcerative Colitis Clinical Trial

Official title:
Optimal Fecal Microbiota Transplant Dosing for Mild to Moderate Ulcerative Colitis

Clinical Trial Summary

This is a prospective unblinded, randomized trial for the use of Fecal Microbiota Transplantation (FMT) for the treatment of Ulcerative Colitis (UC), in combination with or without antibiotic pretreatment.

Clinical Trial Description

This is a prospective open-label, randomized trial for the use of Fecal Microbiota Transplantation (FMT) for the treatment of Ulcerative Colitis (UC), in combination with or without antibiotic pretreatment. This trial involves 11 study visits at UCSF in San Francisco, CA. The routes of administration will be via colonoscopy for all subjects with maintenance therapy administered orally (i.e. using encapsulated FMT) for half of the subjects and per rectum by enema in the other half of the subjects. Additionally, the utility of pretreatment antibiotics will be assessed. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03006809
Study type Interventional
Source University of California, San Francisco
Contact
Status Completed
Phase Phase 1
Start date March 2, 2017
Completion date April 4, 2021
View Details
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