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Efficacy of Treatment With Berberine to Maintain Remission in Ulcerative Colitis

Ulcerative Colitis Clinical Trial

Official title:
Efficacy of Treatment With Berberine to Maintain Remission in Ulcerative Colitis: An Open-label,Randomized,Phase IV Clinical Trial

Clinical Trial Summary

The research aim to find out whether berberine can reduce the annual recurrence rate of ulcerative colitis in remission. A total of 238 patients with ulcerative colitis in remission will be randomly divided into two groups.One will receive regular treatment,and the other group will receive extra oral berberine 300 mg three times daily for a year. The end of the study for every patient is disease recurrence(Mayo Clinic score of 3 points or more ). The primary analysis is annual recurrence rate, and both endoscopy and Mayo Clinic disease activity index scores at the baseline and final assessments.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02962245
Study type Interventional
Source Xijing Hospital of Digestive Diseases
Contact
Status Withdrawn
Phase Phase 4
Start date November 2016
Completion date January 2018
View Details
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