Treatment With Local PPARgamma Ligand in Distal Ulcerative Colitis

Status Recruiting

Clinical Trial Summary

Treatment with PPARgamma ligands have been shown to reduces intestinal inflammation in murine models of colitis. The aim of this study was to evaluate the effect of treatment with local PPARgamma ligand (rosiglitazone) in distal ulcerative colitis.The patients are treated with rosiglitazone enema, once a day, for fourteen days. Disease activity was assessed before and after treatment by endoscopical and clinical activity score.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00309660
Study type	Interventional
Source	Herlev Hospital
Contact	Gitte Pedersen
Phone	+ 45 44883418
Email	gitped01@herlevhosp.kbhamt.dk
Status	Recruiting
Phase	Phase 1/Phase 2
Start date	November 2005
Completion date	June 2007

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