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Type II Diabetes Mellitus clinical trials

View clinical trials related to Type II Diabetes Mellitus.

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NCT ID: NCT04970108 Withdrawn - Clinical trials for Type II Diabetes Mellitus

Efficacy and Safety of Egito Association in the Treatment of Type II Diabetes Mellitus and Hypertension

EGITO
Start date: August 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Egito association in the treatment of type 2 diabetes mellitus and hypertension

NCT ID: NCT04790526 Completed - Clinical trials for Type II Diabetes Mellitus

Dose Response of Eccentric Exercise on Glycemic Control in Type II Diabetes Mellitus

Start date: July 12, 2021
Phase: N/A
Study type: Interventional

The major aim of this project to check the dose response of eccentric exercise in reduction of glycemic index in type II Diabetes Mellitus. This study aim to check the effect of eccentric exercises on Glycemic index, quality of life, strength, exertion, balance and proprioception in type II Diabetes Mellitus patients

NCT ID: NCT04665284 Completed - Clinical trials for Type II Diabetes Mellitus

Safety And Efficacy Of Empagliflozin In Pakistani Muslim Population With Type Ii Diabetes Mellitus

SAFE-PAK
Start date: June 1, 2019
Phase: Phase 4
Study type: Interventional

To compare the safety and efficacy of empagliflozin versus other treatments in Pakistani Muslim population with type II diabetes mellitus.

NCT ID: NCT03912363 Active, not recruiting - Clinical trials for Gestational Diabetes Mellitus

Intrapartum Glycemic Control With Insulin Infusion Versus Rotating Fluids

Start date: November 1, 2019
Phase: N/A
Study type: Interventional

This study will determine whether rotating intravenous (IV) fluid is better than receiving insulin to control a baby's blood sugar after delivery in laboring women with diabetes. A computer will choose the method of controlling the participant's blood sugar while they are in labor.

NCT ID: NCT03907202 Terminated - Clinical trials for Type II Diabetes Mellitus

A Clinical Study to Evaluate the Safety, Tolerability, PK, PD, and Efficacy of KBP-089 in Patients With T2DM

Start date: April 17, 2018
Phase: Phase 1
Study type: Interventional

KeyBioscience is developing KBP-089, a dual activator of both the amylin and calcitonin receptors, for the treatment of type II diabetes mellitus, using a subcutaneous injectable mode of administration. This is a double-blind, placebo-controlled, randomised, multiple-ascending dose phase I trial to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of KBP-089 in patients with type 2 diabetes, who are on stable therapy with metformin. Subjects will receive daily subcutaneous injections in the abdomen over a period of 28 days. The planned maximum doses of KBP-089 to be investigated in the trial are 20 µg in cohort 1, 60 µg in cohort 2, and 150 µg in cohort 3. For cohort 1, the dose is planned to be escalated every 7 ±1 days, and for cohort 2 and cohort 3, every 3 days. Doses may be modified according to individual tolerability, but the dose regimen will not exceed 28 days. The IMP is administered by daily subcutaneous injections taken in the morning before breakfast. The trial is performed in Germany and at least 36 patients will be enrolled in the trial. The trial will be randomised 1:1:1 between maximum doses of KBP-089 of 20 µg, 60 µg, 150 µg and placebo. Within each of the three cohorts, 12 patients will be randomised 3:1 to KBP-089 and placebo.

NCT ID: NCT03615755 Completed - Diabetic Foot Ulcer Clinical Trials

Short Duration Hyperbaric Oxygen Therapy to Improve HbA1c, Leukocyte, and Serum Creatinine

Start date: December 27, 2016
Phase: N/A
Study type: Interventional

The investigators want to evaluate the short duration HBOT can improve glycohemoglobin (HbA1c) levels, leukocyte count, and serum creatinine levels in patients with DFU (diabetic foot ulcer) Wagner 3-4.

NCT ID: NCT03601910 Active, not recruiting - Clinical trials for Type II Diabetes Mellitus

Clinical Study to Compare the Pharmacokinetic Characteristics and Safety Between CKD-380 10mg and D308 10mg

Start date: July 16, 2018
Phase: Phase 1
Study type: Interventional

This study is an open-label, randomized, fasted, single-dose, 2-way crossover study to compare the pharmacokinetic characteristics and safety between CKD-380 10mg and D308 10mg in healthy male adults.

NCT ID: NCT03550378 Completed - Renal Insufficiency Clinical Trials

A Study to Look at the Effect MEDI0382 Has on Blood Sugar in People With Type 2 Diabetes and Kidney Problems and Also to Check That MEDI0382 is Well Tolerated

Start date: June 29, 2018
Phase: Phase 2
Study type: Interventional

A study to look at the effect MEDI0382 has on blood sugar in people with type 2 diabetes and kidney problems and also to check that MEDI0382 is well tolerated.

NCT ID: NCT03084965 Completed - Clinical trials for Type II Diabetes Mellitus

Retrospective Study of Patients With Type 2 Diabetes Mellitus on Dapagliflozin Therapy in Taiwan

Start date: May 12, 2017
Phase:
Study type: Observational

Retrospective Study of Patients With Type 2 Diabetes Mellitus on Dapagliflozin Therapy in Taiwan.

NCT ID: NCT03059719 Completed - Clinical trials for Type II Diabetes Mellitus

Clinical Trial for PB-119 in Subjects With Type 2 Diabetes Mellitus

Start date: April 8, 2015
Phase: Phase 1
Study type: Interventional

This is a randomized, opened, positive drug-controlled (Exenatide, Byetta), sequential parallel group, multiple dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of twelve once-weekly subcutaneous doses of PB-119 to subjects with type 2 diabetes mellitus (T2DM).