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Type A Aortic Dissection clinical trials

View clinical trials related to Type A Aortic Dissection.

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NCT ID: NCT06415630 Completed - Clinical trials for Type A Aortic Dissection

Prediction Models for Postoperative Reintubation in Patients With Acute Aortic Dissection

ADreintubate
Start date: January 1, 2018
Phase:
Study type: Observational

Reintubation is an adverse postoperative complication in patients with Type A aortic dissection (AAD) that correlates to poor outcomes. This study aims to analyze the risk factors associated with reintubation and to create a fully automated score model to predict the incidence of reintubation. A total of 861 patients diagnosed with AAD and undergoing surgical procedures in a single institution between January 2018 and October 2023 were selected in wuhan Union Hospital. Preoperative and postoperative informmation was used for seeking risk factors and build prediction model for postoperative reintubation. Finally, 5 risk factors wasidentified and a nomogram was established for predicting postoperative reintubation in patients with AAD.

NCT ID: NCT05751200 Completed - Clinical trials for Type A Aortic Dissection

Safety and Efficacy of Aortic Root Reinforcement Combined With Vascular Grafts Eversion and built-in Procedure (XJ-procedure) in Patients With Acute Type A Aortic Dissection (ADVANCED-XJ )

Start date: March 1, 2023
Phase:
Study type: Observational

This is a retrospective study based on the data available in our hospital database for ATAAD patients from January 2020 to December 2021. These patients were divided into two groups according to the surgical procedures of aortic root. This study compared baseline data, perioperative and short-term follow-up results between the two groups to evaluate the efficacy and safety of XJ-procedure in ATAAD.

NCT ID: NCT05346497 Completed - Clinical trials for Type A Aortic Dissection

Surgical Management of the Aortic Root and Long-term Outcomes For Acute Type A Aortic Dissection

Start date: January 1, 2005
Phase:
Study type: Observational

The investigators focus on the patients who underwent aortic root surgery for acute type A aortic dissection between 2005.01-2021.11. The patients are divided into 3 groups according to the different aortic root surgical methods(Bentall,David and root reconstruction). Clinical data including age, gender, comorbidities, surgical informations and perioperative informations will be collected. All patients will receive follow-ups in hospital or by telephone. All the informations will be analyzed by SPSS to show the difference of both perioperative and long-term results among different surgical strategies.

NCT ID: NCT04711889 Completed - Clinical trials for Type A Aortic Dissection

Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Ulinastatin) II

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Acute Aortic Syndrome (AAS) is a common feature of acute aortic wall events, including aortic dissection, intramural hematoma, aortic ulceration and aortic trauma, and occurs in up to 35 cases per 100,000 cases per year between the ages of 65 and 75 years. Ulinastatin has antiinflammatory activity and suppresses the infiltration of neutrophils and the release of elastase and chemical mediators from neutrophils. Recent studies have shown that ulinastatin may be cytoprotective against ischemia-reperfusion injury in the liver, kidney, heart, and lung. The authors aim to examine the association between decreased release of inflammatory response to urinary trypsin inhibitor treatment and decreased myocardial and lung injury after acute aortic syndrome surgery.

NCT ID: NCT02164201 Completed - Clinical trials for Thoracic Aortic Aneurysm

Post Market Surveillance Study Evaluating BioFoam Surgical Matrix in Cardiovascular Surgery

Start date: August 2014
Phase: N/A
Study type: Observational

This is a prospective, multicenter, single-arm study designed to collect clinical data to support the safety and effectiveness of BioFoam used as a surgical adjunct to anastomotic hemostasis following cardiovascular surgery. The overall objective of this clinical study is to collect clinical data supporting the safety and effectiveness of BioFoam used as a surgical adjunct to anastomotic hemostasis following cardiovascular surgery. This study is intended as a post-market surveillance (follow-up) study.