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Type 2 Diabetes Mellitus clinical trials

View clinical trials related to Type 2 Diabetes Mellitus.

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NCT ID: NCT04450394 Completed - Clinical trials for Type 2 Diabetes Mellitus

A Phase 2 Study of LY3209590 in Participants With Type 2 Diabetes Mellitus

Start date: July 1, 2020
Phase: Phase 2
Study type: Interventional

The reason for this study is to see if the study drug LY3209590 is safe and effective in participants with type 2 diabetes.

NCT ID: NCT04449120 Completed - Clinical trials for Type 2 Diabetes Mellitus

HOME COOKING: Health Empowerment Strategy in People With Type II Diabetes Mellitus

SUKALMENA
Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Currently, one of the health challenges in the field of public health is to improve the quality of life of people with metabolic diseases, using new strategies that allow to promote healthy eating habits. Within the new strategies that may encourage population improving eating habits, "HOMECOOKING" is proposed as a transforming tool for health, involving culinary skills and knowledge in nutrition. It is suggested as a new paradigm in nutritional education. This project will cover the "HOMECOOKING: cooking and eating at home", as an innovative strategy, aiming to improve the quality of the diet of people with type II diabetes mellitus through an intervention based on cooking workshops. At these sessions, participants will learn easy cooking techniques and tools, in order to acquire culinary competences and to be empowered to prepare healthy dishes. The effect of this intervention programme on the health of the participants will be evaluated through the measurement of biochemical parameters related to the disease (glycosylated haemoglobin, insulin, glucose, among others). In addition, specific compounds known as advanced glycation end products (AGEs) will be measured. The formation of these compounds is associated with the type of food consumed and the culinary techniques that are applied.

NCT ID: NCT04446026 Completed - Clinical trials for Type 2 Diabetes Mellitus

A Randomized, Placebo-controlled Clinical Trial of Teneligliptin as Quadruple Oral Combination Therapy for Type 2 DM After Failure of an Oral Triple Anti-diabetic Regimen

Start date: July 8, 2020
Phase: Phase 4
Study type: Interventional

This is a randomized, placebo-controlled clinical trial of Teneligliptin as quadruple oral combination therapy for type 2 diabetes after failure of an oral triple anti-diabetic regimen. Patients with uncontrolled type 2 diabetes (7.1% ≤ HbA1c ≤ 9%) prescribed with triple combination of oral antidiabetic drugs more than 12 weeks with sufficient doses (metformin >= 1000mg/d, Glimepiride >=4 mg/day, Gliclazide >= 60 mg/day, SGLT-2 inhibitor with approved dose by Korea FDA) will be included. Using randomization, patients would take either teneligliptin (20mg) or placebo for 12 weeks. After 12 weeks of trial, all patients would receive teneligliptin for another 12 weeks. As outcomes, changes in HbA1c and fasting plasma glucose at 12th and 24th weeks compared with at baseline, and proportions of patients who achieved a glycemic goal (HbA1c <=7%) at 12th and 24th weeks will be evaluated.

NCT ID: NCT04445714 Completed - Clinical trials for Type 2 Diabetes Mellitus

To Assess Safety of Fixed Dose Combination of Dapagliflozin and Saxagliptin in Type 2 Diabetes Mellitus Patients

Start date: April 7, 2021
Phase: Phase 4
Study type: Interventional

A prospective, multicenter, phase -IV study to assess the safety of fixed dose combination of dapagliflozin and saxagliptin in Indian Type 2 Diabetes Mellitus (T2D) patients.

NCT ID: NCT04436822 Completed - Clinical trials for Type 2 Diabetes Mellitus

Evaluation of Updated Continuous Glucose Monitoring (CGM) Form Factor in Adults, Adolescents and Pediatrics

Start date: July 15, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to demonstrate the performance of the Disposable Sensor (DS5) in subjects age 2 - 80 years, for the span of 170 hours (7 days).

NCT ID: NCT04431687 Completed - Clinical trials for Type 2 Diabetes Mellitus

A Clinical Trial to Investigate the Pharmacokinetic Drug Interaction and Safety of CKD-501, D759 and D150 (CKD-393)

Start date: June 15, 2020
Phase: Phase 1
Study type: Interventional

A Clinical trial to investigate the pharmacokinetic drug interaction and safety of CKD-501, D759 and D150

NCT ID: NCT04431141 Completed - Clinical trials for Type 2 Diabetes Mellitus

Pharmacokinetic Drug Interaction Between Teneligliptin and Empagliflozin

Start date: September 15, 2020
Phase: Phase 1
Study type: Interventional

This study is to evaluate pharmacokinetic drug interaction between teneligliptin and empagliflozin in healthy adults.

NCT ID: NCT04429503 Active, not recruiting - Clinical trials for Type 2 Diabetes Mellitus

Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease

PHOTON
Start date: June 29, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The primary objective of the study is to determine if treatment with high-dose aflibercept (HD) at intervals of 12 or 16 weeks provides non-inferior best corrected visual acuity (BCVA) compared to aflibercept dosed every 8 weeks. The secondary objectives of the study are as follows: - To determine the effect of HD vs. aflibercept on anatomic and other visual measures of response - To evaluate the safety, immunogenicity, and pharmacokinetics (PK) of aflibercept

NCT ID: NCT04426708 Completed - Clinical trials for Type 2 Diabetes Mellitus

A Clinical Study to Access the Pharmacokinetics of HMS5552 in Hepatic Impaired Subjects and Healthy Volunteers

Start date: February 18, 2019
Phase: Phase 1
Study type: Interventional

The objectives of this study is to access the pharmacokinetics and safety of HMS5552 in single dose in mild and moderate hepatic impaired subjects and matched healthy adult subjects.

NCT ID: NCT04390295 Recruiting - Clinical trials for Type 2 Diabetes Mellitus

Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 Diabetes

Start date: November 2, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to obtain information on efficacy and safety of SHR3824 with metformin over 24 weeks and 52 weeks in metformin monotherapy poorly glycemic controlled chinese Type 2 Diabetes. Efficacy and safety will be evaluated by comparing the effect of SHR3824 with metformin to placebo with metformin when given in oral doses.