Type 1 Diabetes Clinical Trial
Official title:
An Open, Mono-centre Pilot Study to Investigate a Novel Technique to Establish Glycaemic Control for Critically Ill Patients, Tested in Type 1 Diabetic Subjects for a Period of 30 Hours.
The EU funded project CLINICIP (Closed Loop Insulin Infusion for Critically Ill Patients)
aims to develop a low-risk monitoring and control device which allows maintaining metabolic
control in intensive care units. A system will be developed comprising three subsystems: a
body interface for the delivery of biofluids, biosensors for the determination of glucose
concentration in these biofluids and an adaptive control algorithm that generates advice and
thus represents a decision support system with respect to insulin infusion rate to establish
glycaemic control in critically ill patients. Within a closed loop system, intensified
insulin treatment will make use of the calculations leading to external regulation of
glucose.
It is the aim of this study to evaluate the feasibility to establish glycaemic control in
type 1 diabetic subjects over a period of 30 hours by manually combining these three -
previously tested - subsystems (ABS System, extracorporeal online glucose sensor and a
laptop-based computer algorithm).
n/a
Time Perspective: Prospective
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