Type 1 Diabetes Mellitus Clinical Trial
Official title:
Liraglutide as Additional Treatment in Patients With Type 1 Diabetes Mellitus, a Retrospective Chart Review
Evaluating the use of Liraglutide in patients with Type 1 Diabetes.
This investigation will be a retrospective chart review of in type 1 diabetics who have been
treated with liraglutide. The study will be conducted at Diabetes-Endocrinology Center of
WNY at Millard Fillmore Hospital, affiliated to the State University of New York at Buffalo.
Study Population: 40 patients with type 1 diabetes on treatment with either continuous
subcutaneous insulin infusion (CSII; also known as insulin pump) or multiple (four or more)
injections of insulin per day on continuous glucose monitoring system (CGMS) will be
included in the study. These patients with type 1 diabetes have been treated with
liraglutide in addition to insulin. The investigators would retrospectively review their
charts to evaluate decreases in fasting, postprandial and the overall mean glucose
concentrations.
The investigators will compare the mean fasting, the mean weekly glucose and the standard
deviation of weekly blood glucose concentrations as recorded by continuous glucose
monitoring prior to and following one week and 12 weeks of treatment with liraglutide daily.
In addition, the investigators will compare the time spent at glucose concentrations >150
and 200mg/dl and <70 and <40 mg/dl. HbA1c levels before and after 12 weeks of treatment with
liraglutide daily will be compared.
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