Effect of Pioglitazone on the Course of New Onset Type 1 Diabetes Mellitus

Status Completed

Clinical Trial Summary

A study to examine the effect of pioglitazone on the course of new onset type 1 diabetes mellitus.

Clinical Trial Description

Thiazolidinediones have been shown to reduce the development of diabetes mellitus in animal models of type 1 diabetes and to reduce the death of beta cells (cells that make insulin) in petri dishes. Pioglitazone is a thiazolidinedione currently approved for the treatment of type 2 diabetes. This study explores the question of whether pioglitazone can preserve beta cell function in patients with recently diagnosed type 1 diabetes mellitus. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00545857
Study type	Interventional
Source	Stony Brook University
Contact
Status	Completed
Phase	Phase 1
Start date	June 2002
Completion date	May 2012

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