Drainage of Tuberculous Pleural Effusions

Tuberculous Pleurisy Clinical Trial

Official title: Drainage of Tuberculous Pleural Effusions

Status Completed

Clinical Trial Summary

Tuberculous (TB) pleurisy can cause clinical symptoms and pleural fibrosis with resultant residual pleural thickening (RPT). Therapeutic thoracentesis or initial complete drainage in addition to anti-TB drugs have been tried to rapidly relieve dyspnea caused by effusion and to decrease the occurrence of RPT. However, contradictory results are reported without clear reasons. The researchers' hypothesis is that, in addition to anti-TB medications, early effective evacuation of inflammatory exudates with or without fibrinolytic agents may hasten resolution of pleural effusion, reduce the occurrence of RPT and finally improve long-term functional outcome in patients with TB pleurisy.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Pleural Effusion
• Tuberculosis
• Tuberculosis, Pleural
• Tuberculous Pleurisy

• NCT number: NCT00524147
• Study type: Interventional
• Source: Taipei Medical University Hospital
• Status: Completed
• Phase: N/A
• Start date: October 2003
• Completion date: December 2006