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Validating the Use of Blood Transcriptomic Signatures for the Diagnosis of Active Pulmonary Tuberculosis — ISIT-TB  

TUBERCULOSIS, PULMONARY Clinical Trial

Official title:
Validating the Use of Blood Transcriptomic Signatures for the Diagnosis of Active Pulmonary Tuberculosis With the ISIT-TB Prototype in Adults Living in a High Burden Setting

Clinical Trial Summary

ISIT-TB Prototype is a diagnostic assay based on a transcriptional blood signature suggestive of the detection of Mycobacterium tuberculosis.

Clinical Trial Description

This device will be investigated for use as a screening tool to facilitate diagnosis of ATB in conjunction with risk assessment, clinical context and diagnostic information. Whole blood samples will be collected in Tempus™ Blood RNA Tubes and processed on an automatized platform. The detection of a combination of under or over-expressed selected genes, constituting a transcriptional signature, will allow the characterization of ATB. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04995406
Study type Observational
Source BioMérieux
Contact
Status Completed
Phase
Start date January 3, 2022
Completion date December 31, 2023
View Details
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