Acute Presentation and Management of Abdominal Tuberculosis: A Ten-year Experience at a Tertiary Care Center in Pakistan

Tuberculosis; Abdomen Clinical Trial

Official title:

Acute Presentation and Management of Abdominal Tuberculosis: A Ten-year Experience at a Tertiary Care Center in Pakistan

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03918226
• Other study ID #: s16
• Status: Completed
• Phase: N/A
• Start date: May 1, 2008
• Est. completion date: April 30, 2018

Study information

• Verified date: April 2019
• Source: Services Hospital, Lahore
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

A prospective interventional study was conducted in Services Instituton of Medical Sciences all patients who underwent emergency laparotomy from 2008-2018 due to abdominal tuberculosis. Data were analyzed using SPSS version 21

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: April 30, 2018
• Est. primary completion date: April 30, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 12 Years to 90 Years

Eligibility

Inclusion Criteria:

• Both sexes and age between years and 90 years

• Patients presenting with acute abdomen and who underwent exploratory laparotomy

• Patients who diagnosis confirmed on biopsy (caseating granulomas)

Exclusion Criteria:

• Peritoneal tuberculosis

• Other causes of acute abdomen (Typhoid perforation)

• Patients diagnosed with abdominal tuberculosis and on conservative management

Related Conditions & MeSH terms

• Tuberculosis
• Tuberculosis; Abdomen

Intervention

Procedure:
• exploratory laparotomy
Patients presenting with acute abdomen were operated. Exploratory Laparotomy of patients was done. Further procedure was done according to peroperative findings. Ileostomy for perforation of gut, stricturoplasty for strictutre, biopsy for mesentric lymphadenopathy

Locations

Country	Name	City	State
Pakistan	Services hospital	Lahore	Punjab

Sponsors (1)

Lead Sponsor	Collaborator
Services Hospital, Lahore

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Percentage of patients who develop complications after surgery	Complications of surgery like leakage of gut content, enterocutaneous fistula, intestinal obstruction	9 months
Primary	Percentage of patients who develop recurrence of abdominal tuberculosis (elevated ESR, CT scan findings of abdominal tuberculosis)	Recurrence of abdominal tuberclosis assessed by ESR, CT scan Abdomen, Biopsy	1 year
Primary	Mortality rate	death due to postoperative complications	9 months