New Formulation and Food Effect Study of BIIB074

Trigeminal Neuralgia (TN) Clinical Trial

Official title:
A Phase 1, Open-label Study to Evaluate the Relative Bioavailability of Two Formulations of BIIB074 and to Assess the Effect of Food on BIIB074 Pharmacokinetics in Healthy Subjects

Status Completed

Clinical Trial Summary

The primary objectives of the study are to assess the relative bioavailability of the BIIB074 direct compression formulation (DCF) to the BIIB074 roller compaction formulation (RCF) and to determine the effect of a high-fat meal on the pharmacokinetics (PK) of the BIIB074 DCF. The secondary objective of the study is to assess the safety and tolerability of BIIB074 administered as the DCF following single oral dose administration in healthy participants.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02951221
Study type	Interventional
Source	Biogen
Contact
Status	Completed
Phase	Phase 1
Start date	December 2016
Completion date	February 2017

View Details

See also
	Status	Clinical Trial	Phase
	Completed	`NCT03778177` - Neurophysiologic Signatures of Trigeminal Neuralgia Pain	N/A
	Completed	`NCT06174818` - Pulsed Radiofrequency Treatment Of the Gasserian Ganglion for tRigeminal nEuralgia: a retroSpective Study