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Treatment Adverse Effect clinical trials

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NCT ID: NCT04470440 Completed - Prognosis Clinical Trials

Thyroid Dysfunction and Nivolumab Reponse in NSCLC

THYRONIVO
Start date: October 22, 2019
Phase:
Study type: Observational

This is an observational, retrospective and monocentric study, conducted at the university Hospital of Brest The primary objective is to assess the association between the occurrence of thyroid dysfunction in patients treated with Nivolumab® for a non-small cell lung cancer and prognosis and therapeutic response The second objective is to assess prognosis and therapeutic response according to severity and subtype of thyroid dysfunction

NCT ID: NCT02840877 Completed - Tuberculosis Clinical Trials

The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes

Start date: May 16, 2017
Phase: N/A
Study type: Interventional

After HIV/AIDS, tuberculosis (TB) remains the second leading cause of death due to an infectious disease globally. Retrospective studies from many countries, including the United States and South Africa, have consistently reported that in addition to having a higher burden of TB disease, patients with problem alcohol use have worse TB treatment outcomes. This prospective study will attempt to clarify both behavioral and biologic causal mechanisms underlying the deleterious effects of problem alcohol use on TB treatment response.