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The Effect of Single Dose D-Cycloserine on Cognitive Outcome in Moderate Traumatic Brain Injury (TBI) Patients — DCS  

Traumatic Brain Injury Clinical Trial

Official title:
The Effect of Single Dose D-Cycloserine on Cognitive Outcome in Moderate TBI Patients

Clinical Trial Summary

In this study of patients with moderate traumatic brain injury with frontal brain contusions patients will be randomized to treatment with a single dose of either D-cycloserine or placebo given 48-72 hours after injury.

Patients will undergo intensive neurocognitive testing at 3 and 6 months after injury to assess whether treatment with a single dose of D-cycloserine improves cognitive outcome after moderate brain injury.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01343862
Study type Interventional
Source Hadassah Medical Organization
Contact Guy Rosenthal, MD
Phone 972-2-677-7092
Email rosenthalg@hadassah.org.il
Status Not yet recruiting
Phase Phase 2
Start date August 2011
Completion date May 2014
View Details
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