Traumatic Brain Injury Clinical Trial
Official title:
PC-Based Cognitive Rehabilitation for TBI
The investigators evaluated whether it was possible to improve the measurement of memory,
attention, and executive function in patients who have suffered traumatic brain injury
through the use of computer-based testing.
Note: the original design of the study was altered due to failure to recruit sufficient
numbers of patients who were willing to undergo prolonged cognitive training.
Here we describe a series of computer-based tests that were used to evaluate memory,
attention, and executive function in large groups of control subjects and in patients with
chronic mild and moderate/severe TBI. This extensive battery of neuropsychological tests
(NPTs) and subjective rating scale measures were obtained at study entry from the TBI
cohort. NPT and rating scale data were compared to those obtained from control subjects to
characterize the cognitive deficits following mild, moderate and severe TBI. .
Normative data were obtained by regressing the influences of age, education, and computer
use on scores to create normed z-scores on different NPTs,. We hypothesized that patient
with TBI would show deficits on tests of memory, attention, and executive function relative
to their predicted z-scores (based on the aforementioned regression functions) and that
deficits would be more pronounced in patients with severe TBI than in patients with mild
TBI.
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Observational Model: Ecologic or Community, Time Perspective: Cross-Sectional
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