Traumatic Brain Injury (TBI) Clinical Trial
Official title:
A Phase 1, Randomised, Double-Blind, Placebo-Controlled, First in Human Study of the Safety, Tolerability and Pharmacokinetics of a Single Dose of PRV-002 in Healthy Volunteers.
The purpose of this study is to assess the safety, tolerability, and pharmacokinetics of different dose levels of PRV-002 in Health Volunteers
This Phase 1 study is designed to assess the safety, tolerabilty and pharmcokinetics of different dose levels of PRV-002 in Healthy Volunteers. The study will evaluate 3 dose levels of the investigational product, PRV-002, in 3 cohorts of 8 healthy volunteers per cohort. In each cohort, 6 volunteers will receive the investigational product and 2 volunteers will receive placebo. Dose levels will be evaluated in a sequential manner starting at the lowest dose level. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02878577 -
Monitoring the Alterations That Occur in the Brain Following Traumatic Brain Injury
|
||
Active, not recruiting |
NCT02918994 -
LearningRx Cognitive Training for TBI
|
N/A | |
Completed |
NCT02524067 -
Modified Environment for Agitation in Patients With TBI
|
N/A | |
Completed |
NCT01760785 -
Valproate for Mood Swings and Alcohol Use Following Head Injury
|
N/A | |
Not yet recruiting |
NCT04003285 -
Allopregnanolone in Chronic Complex Traumatic Brain Injury
|
Phase 2 | |
Completed |
NCT01750268 -
Topiramate Treatment of Hazardous and Harmful Alcohol Use in Veterans With TBI
|
Phase 4 | |
Recruiting |
NCT01512524 -
Hormonal Deficiency in the Quality of Life of Patients With Traumatic Brain Injury
|
N/A | |
Completed |
NCT04796207 -
The Effects of Fish Oil Supplementation on the Brain Health of Collegiate Football Athletes
|
N/A | |
Completed |
NCT02657135 -
Targeted Evaluation, Action, & Monitoring of Traumatic Brain Injury
|
N/A | |
Completed |
NCT01956136 -
Efficacy and Neural Basis of Music-based Neurological Rehabilitation for Traumatic Brain Injury
|
N/A | |
Withdrawn |
NCT02356861 -
LED Light Therapy to Improve Cognitive & Psychosocial Function in TBI-PTSD Veterans
|
N/A | |
Recruiting |
NCT04930146 -
Functional Recovery Effect of Bloodletting Puncture at Jing-well Points on Acute Brain Injury Patients
|
N/A | |
Not yet recruiting |
NCT05675423 -
Imaging Characterization of the Biomechanical Coupling of Brain and Skull
|
||
Withdrawn |
NCT01891383 -
Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired Military Personnel
|
||
Completed |
NCT02764983 -
Occupational Therapy Driving Intervention for Returning Combat Veterans.
|
N/A | |
Withdrawn |
NCT01779427 -
Attention Intervention Management
|
N/A | |
Completed |
NCT01118195 -
Executive Dysfunction & Suicide: An Exploration Of Risk Factors In Traumatically Brain Injured Veterans
|
N/A | |
Completed |
NCT01547780 -
Translocator Protein and Inflammation After Traumatic Brain Injury
|
Phase 1/Phase 2 | |
Recruiting |
NCT03874208 -
Prediction for Coma Recovery With Comaweb
|
N/A | |
Completed |
NCT03314584 -
Managing MTBI-related Headaches With rTMS
|
N/A |