Discriminant Ability of the Shock Index, Modified Shock Index, and Reverse Shock Index Multiplied by the Glasgow Coma Scale on Mortality in Adult Trauma Patients: A PATOS Study

Trauma Clinical Trial

Official title:

Discriminant Ability of the Shock Index, Modified Shock Index, and Reverse Shock Index Multiplied by the Glasgow Coma Scale on Mortality in Adult Trauma Patients: A PATOS Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05549986
• Other study ID #: 21MMHIS389e
• Status: Completed
• Start date: January 1, 2016
• Est. completion date: December 31, 2020

Study information

• Verified date: September 2022
• Source: Mackay Memorial Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

We evaluated a cohort of adult trauma patients transported to emergency departments. The first vital signs were used to calculate the SI, MSI, and rSIG. The areas under the receiver operating characteristic curves (AUROCs) and test results were used to compare the discriminant performance of the indices on short-term mortality and poor functional outcome. A subgroup analysis of geriatric patients, traumatic brain injury, penetrating injury, and non-penetrating injury was performed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 105641
• Est. completion date: December 31, 2020
• Est. primary completion date: December 31, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adult patients (=18 years) EMS-transported from January 2016 to December 2020

Exclusion Criteria:

• Patients with missing entries of age, sex, triage, SBP, DBP, HR, or GCS were excluded.

• Entries with missing records of in-hospital mortality or 30-day mortality were excluded from the short-term mortality cohort analyses.

• Patients without a Modified Rankin Scale (MRS) record at discharge were excluded from the functional outcome cohort analyses.

Related Conditions & MeSH terms

• Morality
• Shock
• Shock, Traumatic
• Trauma
• Wounds and Injuries

Intervention

Other:
• Observational
Observational

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Mackay Memorial Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Discriminant power of SI, MSI, and rSIG on short-term mortality for adult traumatic patients	AUROC in associated with short-term mortality with SI, MSI, rSIG	30 days
Secondary	Discriminant power of SI, MSI, and rSIG on functional outcome for adult traumatic patients	AUROC in associated with functional outcome with SI, MSI, rSIG	We defined no symptoms, no significant disability, slight disability, and moderate disability (MRS 0-3) as favorable functional outcomes and moderately severe disability, severe disability, and death (MRS 4-6) as poor functional outcomes