Immune Response to Influenza Vaccine in Islet Cell Transplant Recipients

Status Completed

Clinical Trial Summary

Influenza virus is an important cause of morbidity in the transplant population and can lead to viral and bacterial pneumonia. Although the annual influenza vaccine is recommended for organ transplant patients, studies have shown that the standard inactivated influenza vaccine has poor immunogenicity in this population. The investigators plan to test the humoral response to vaccination and look at HLA upregulation

Clinical Trial Description

OBJECTIVE AND HYPOTHESIS

- To test the specific humoral response of the influenza vaccine after islet cell transplantation

- To test the production of HLA alloantibodies after vaccination. ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Transplant

Clinical Trial Details

NCT number	NCT01149382
Study type	Observational
Source	University of Alberta
Contact
Status	Completed
Phase	N/A
Start date	August 2010
Completion date	December 2011

View Details

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