Clinical Trials Logo
  1. Home
  2. Transplant
  3. NCT00242099

Clinical Utility of Monitoring for Human Herpesvirus-6 (HHV-6) and Human Herpesvirus-7 (HHV-7) After Liver Transplant

Transplant Clinical Trial

Official title:
The Clinical Utility of Monitoring for Human Herpesvirus-6 (HHV-6) and Human Herpesvirus-7 (HHV-7) After Liver Transplant: A Randomized Trial

Clinical Trial Summary

Human herpesvirus-6 (HHV-6) and -7 (HHV-7) infections are common after transplantation. Such infections may predispose transplant patients to other infections, contribute to a recurrence of hepatitis C virus, and affect rejection and function of the transplanted liver. Given the significant clinical impact of these viruses, routine laboratory monitoring may be beneficial by identifying patients who have persistent or high levels of infection. In these patients, immunosuppressive medications could be adjusted, or antiviral medications administered. There are currently no randomized trials that address this important question. This prospective, randomized trial will analyze whether routine laboratory monitoring for HHV-6 and -7 is clinically useful, and whether it would improve overall outcomes in transplant recipients.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00242099
Study type Interventional
Source University Health Network, Toronto
Contact
Status Completed
Phase Phase 4
Start date February 2005
Completion date November 2007
View Details
See also
  Status Clinical Trial Phase
Active, not recruiting NCT05047068 - OCS Heart Perfusion Post-Approval Registry
Completed NCT03455062 - Fertility Study of Women Who Received Organ Transplantation N/A
Terminated NCT05033548 - Technology Enabled And Molecular Monitoring of the Allograft and Transplant rEcipient
Recruiting NCT04182607 - Donor Outcomes Following Hand-Assisted And Robotic Living Donor Nephrectomy: A Retrospective Review
Completed NCT01022905 - Vaccine Responses to Influenza A H1N1/09 Immunization in High-risk Patients Phase 4
Completed NCT00436384 - Cell Mediated Immunity and the Prediction of CMV Infection In Solid Organ Transplant Recipients Phase 4
Active, not recruiting NCT03691220 - Improving Medication Adherence in Adolescents Who Had a Liver Transplant N/A
Completed NCT00571818 - The Prospective Evaluation of Pancreatic Function in Pancreas Transplant Recipients N/A
Terminated NCT00884039 - Anecortave Acetate Injection to Treat Steroid-responsive Intraocular Pressure Increase in Cornea Transplant Patients N/A
Completed NCT00677677 - Safety and Immunogenicity of Human Papillomavirus (HPV) Vaccine in Solid Organ Transplant Recipients Phase 3
Completed NCT03860818 - Improving Transplant Medication Safety Through A Technology and Pharmacist Intervention N/A
Recruiting NCT04626167 - Concomitant Renal and Urinary Bladder Allograft Transplantation Early Phase 1
Completed NCT01389804 - Parents of Pediatric Solid Organ Transplant Recipients: Transition to Home and Chronic Illness Care N/A
Recruiting NCT04390724 - Optimizing Y90 Therapy for Radiation Lobectomy
Not yet recruiting NCT04690036 - PD-1 Antibody for Reactive EBV After BMT Early Phase 1
Active, not recruiting NCT00152802 - Pneumonia Vaccine in Liver Transplant Recipients: a Booster Strategy Using a Conjugate Vaccine Phase 4
Not yet recruiting NCT05951231 - Liver Transplantation After ex Vivo Liver Perfusion N/A
Recruiting NCT05717842 - Simultaneous Prospective Kidney Transplant Assessment in Combined Liver Kidney Candidates
Recruiting NCT05655546 - ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals N/A
Recruiting NCT06161454 - Xofluza-Wearables Feasibility-Study Phase 4