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Extracellular Vesicles and Endothelial Function in Transgender Subjects — Evinge  

Transgenderism Clinical Trial

Official title:
Effects of Plasma Extracellular Vesicles on Endothelial Function in Transgender Subjects

Clinical Trial Summary

Cardiovascular diseases are the leading cause of mortality. In women, the prevalence of cardiovascular diseases is lower and the presentation of coronary events often atypical. The lack of evidence is related in part to the methodology of studies not considering sex as an essential biological variable. Hormonal treatment is prescribed in transgender subjects to promote the development of sexual characteristics of the desired sex. Early cardiovascular effects of hormonal treatment have been reported in transgender men, while long-term mortality is higher in transgender women. The aim of this project is to study the effects of gender affirming hormonal treatment on arterial stiffness in young transgender subjects followed at the University Hospital of Nancy.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04971447
Study type Interventional
Source Central Hospital, Nancy, France
Contact
Status Not yet recruiting
Phase N/A
Start date August 2022
Completion date January 2024
View Details
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