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Clinical Trial Summary

This project will evaluate the effect of gender-affirming testosterone treatment on how other medications are processed by the body.

Clinical Trial Description

Gender-affirming hormone therapy may include testosterone, a hormone that the body creates and uses naturally. Testosterone is prepared as a medication that patients may take to increase hormone levels. Changes in testosterone concentrations in the body may affect how the body processes other medicines. The purpose of this study is to find out how testosterone therapy affects a single tracer dose of approved medicines in the blood (midazolam, digoxin, and acetaminophen) and to confirm testosterone treatment does not affect natural bacterial in the gut. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05116293
Study type Observational
Source University of Washington
Contact Lauren Cirrincione, MPH, PharmD
Phone 650-353-7782
Email [email protected]
Status Recruiting
Start date May 1, 2021
Completion date June 1, 2022

See also
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