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Transgender Persons clinical trials

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NCT ID: NCT05924217 Recruiting - Cervical Cancer Clinical Trials

Gynecology Beyond Gender: Cervical Cancer Screening in Transgender Men in France

GYDECAT
Start date: January 2, 2024
Phase:
Study type: Observational

In France, cervical cancer screening is the subject of a national screening programme organized for all asymptomatic individuals aged 25 to 65 years with a cervix. The latter contributes greatly to the prevention and early treatment of this disease, whose public health challenge is recognized worldwide. One of the objectives of this programme is to reduce inequalities in access. Transgender men, i.e. individuals assigned to the female gender at birth but identifying with the male gender, are concerned by this screening as long as they still have a cervix, according to the same modalities as for cisgender women. However, they are often excluded from health care, including organized screening programs. Gender change in civil status is one of the obstacles. The provision of gynaecological care is sometimes inadequate. The lack of knowledge of health professionals and the problems of discrimination that transgender people may face reduce the chances of having equitable access. This survey aims to explore the perception that transgender men have of cervical cancer screening and to identify the challenges they face, the obstacles and the levers to access this prevention program.

NCT ID: NCT05469204 Recruiting - Transgender Persons Clinical Trials

Effect of Estrogen Treatment on Drug Metabolism and Transport

Start date: November 1, 2022
Phase:
Study type: Observational

This project will evaluate the effect of gender-affirming estrogen treatment on how other medications are processed by the body.

NCT ID: NCT05166083 Recruiting - Gender Dysphoria Clinical Trials

Investigation of the Perceptual and Acoustic Voice in Trans Man

Start date: March 11, 2022
Phase:
Study type: Observational [Patient Registry]

The aim of the study is to follow acoustic and perceptual voice changes in trans men during hormone therapy and to examine the relationship between psychosocial and vocal characteristics and testosterone measured in routine follow-up in accordance with international follow-up guidelines.

NCT ID: NCT04515472 Recruiting - Transgender Persons Clinical Trials

Effect of Gender Affirming Hormone Therapy on Glucose Metabolism

Start date: June 17, 2020
Phase: Early Phase 1
Study type: Interventional

The study will test: 1. whether estrogen treatment in transwomen is associated with improved insulin sensitivity and beta cell function 2. whether testosterone treatment in transmen is associated with worsening insulin sensitivity and beta cell function 3. whether estrogen therapy leads to enhanced immune response in older transwormen

NCT ID: NCT04478760 Recruiting - Clinical trials for Hormone Replacement Therapy

Trans & Non-binary Reference Intervals While on Hormone Therapy Study

TransRIHTS
Start date: April 13, 2021
Phase:
Study type: Observational

This study will find out what the reference intervals are for common blood tests in transgender people taking hormone therapy. Reference intervals help doctors interpret blood test results. They are expressed as two numbers, and most normal results fall between them. If a results fall outside of them, it may be because of a disease. Some blood tests are also affected by normal difference between people, such as age, sex or ethnicity. For these tests, different reference intervals are given for each group of people. Having accurate reference intervals benefits patients because it allows doctors to identify disease faster. Transgender people have a gender identity which does not match their sex characteristics at birth. Gender identity is the feeling of being a gender, and sex is the biological aspects of growing up male or female. Transgender people may use hormone therapy to help change their appearance to fit their gender identity. This involves taking either oestrogen or testosterone. For blood tests which are affected by sex, it is not clear what reference intervals should be used for transgender people who are on hormone therapy. This is because they have a mixture of male and female sex characteristics. Answering this question will allow doctors to identify disease in them faster. The study will take place at cliniQ, at King's College Hospital, which provides health services to transgender people. It will recruit healthy transgender people who attend the clinic for blood tests to monitor their hormone therapy. Participants will fill out a questionnaire, give a urine sample, then have their appointment as normal. Extra tests will also be performed on their blood sample. The aim is to recruit 240 participants. Participant's tests results will then be used to calculate reference intervals. The study is funded by Viapath Group LLP.