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Tracheostomy clinical trials

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NCT ID: NCT02469909 Recruiting - Tracheostomy Clinical Trials

Comparison Between Immediate and Gradual Decannulation

Start date: June 2015
Phase: N/A
Study type: Interventional

The investigators propose to examine the feasibility and safety of immediate (single stage) decannulation in adult patients in a controlled randomized trial. Patients who will be found fit for decannulation after an otolaryngologist and intensive care specialist assessment will be randomized into two groups: immediate decannulation and gradual decrease in cannula size. Both groups of patients will be monitored after decannulation and in the outpatient clinic for any complications following the procedure.

NCT ID: NCT02116608 Completed - Tracheostomy Clinical Trials

Treatment of Tracheostomy Granulomas

Start date: September 2014
Phase: Phase 4
Study type: Interventional

This study plans to learn more about the different ways used to treat tracheostomy granulomas. Investigators want to see which standard of care method (steroid application, silver nitrate, or betadine) is more successful in treating tracheostomy granulomas.

NCT ID: NCT01976819 Completed - Tracheostomy Clinical Trials

Clinical Assessment of New Speaking Valve With Heat and Moisture Exchanger (HME) for Tracheotomized Patients

Start date: October 2013
Phase: N/A
Study type: Interventional

This clinical investigation addresses the performance of a re-designed The current study aims to investigate the next version of the TW speaking valve, in combination with both a 15mm and 22mm HME cassette.

NCT ID: NCT01356719 Completed - Tracheostomy Clinical Trials

Scoring Method for Describing the Position of a Tracheostomy Tube

Start date: July 2011
Phase:
Study type: Observational

Tracheostomies are artificial airway devices inserted into the neck. They can become displaced and lead to patient harm. Other than external visual inspection, there is no currently described system for describing the position of a tracheostomy tube within the airway. The investigators propose to undertake endoscopic inspection of the tracheostomy tube with a small fibre-optic camera from above and also through the tube to visualise its position within the airway. The investigators will take anonymised paired images and then score these using 6 different scoring systems. The investigators will determine which scoring system provides the simplest and most reproducible scores between 6 blinded assessors. A clinically useful scoring system could be used in future to predict problems with tracheostomy positioning.

NCT ID: NCT00978783 Completed - Clinical trials for Mechanical Ventilation

Speech Effects of a Speaking Valve Versus External Positive End-expiratory Pressure (PEEP) in Tracheostomized Ventilator-Dependent Neuromuscular Patients

Start date: December 2008
Phase: Phase 2/Phase 3
Study type: Interventional

Background: Many patients with respiratory failure related to neuromuscular disease receive chronic invasive ventilation through a tracheostomy. Improving quality of life, of which speech is an important component, is a major goal in these patients. The investigators compared the effects on breathing and speech of low-level positive end-expiratory pressure (PEEP, 5 cm H2O) and of a Passy-Muir speaking valve (PMV) during assist-control ventilation. Methods: Flow will be measured using a pneumotachograph. Microphone speech recordings were subjected to both quantitative measurements and qualitative assessments; these last consisted of a perceptual score and an intelligibility score determined by two speech therapists using a French adaptation of the Frenchay Dysarthria Assessment.

NCT ID: NCT00956540 Completed - Tracheostomy Clinical Trials

Does Deflating the Tracheal Cuff Shorten Weaning Time?

Start date: December 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether deflating the tracheal cuff in tracheostomized patients, during disconnections from ventilatory support along the weaning phase shortens the weaning time.

NCT ID: NCT00323986 Terminated - COPD Clinical Trials

Azithromycin Treatment of Patients With Chronic Obstructive Pulmonary Disease (COPD) and Tracheostomy

Start date: October 2004
Phase: Phase 2
Study type: Interventional

Aims of the study - to evaluate the rate of enteric gram negative bacteria colonization in tracheotomised COPD patients - to evaluate the effect of azithromycin long-term treatment on Pseudomonas aeruginosa colonization and colony counts, and on reduction of the number of exacerbations/hospitalisations, antibiotic courses and steroid use. - to evaluate the Quality of Life of patients treated and not treated with azithromycin, using a validate Italian version of St George questionnaire - to evaluate the rate of chronic colonization with atypical pathogens - to evaluate the safety and tolerability of a long-term treatment with azithromycin, including a survey on possible bacterial antibiotic resistance pattern variations