Tourniquet Clinical Trial
Official title:
Gradual Deflation of Thigh Tourniquet for Attenuation of Hemodynamic Post-tourniquet Response in Old Patients :Randomized Control Study
Verified date | July 2019 |
Source | Cairo University |
Contact | yasmin ibrahim |
Phone | 01006719987 |
yalnaby[@]yahoo.com | |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Deflation of the pneumatic tourniquet used in lower limb surgery is usually associated with hemodynamic instability, metabolic and respiratory changes. These changes are usually tolerated by young, healthy patients; However, these complications are risky for elderly and cardiac patients. The aim of this study is to assess the effect of gradual deflation of thigh tourniquet on the hemodynamics and arterial blood gases compared to the usual practice
Status | Not yet recruiting |
Enrollment | 81 |
Est. completion date | January 2020 |
Est. primary completion date | January 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 50 Years to 100 Years |
Eligibility |
Inclusion Criteria: - scheduled for elective orthopedic lower limb surgery under pneumatic tourniquet Exclusion Criteria: - BMI =35Kg/ m2 - patients with unstable angina, left ventricular dysfunction , cerebrovascular disease ,bleeding disorders - contraindication to tourniquet insertion - patients requiring massive intraoperative blood transfusion (Blood loss more than 50% of the patients' blood volume (70 ml/Kg) ). |
Country | Name | City | State |
---|---|---|---|
Egypt | Cairo university | Cairo |
Lead Sponsor | Collaborator |
---|---|
Cairo University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | mean arterial blood pressure | The lowest mean arterial blood pressure during a 15-minute period after starting deflation of the tourniquet. | 15 minutes after start of deflation of cuff | |
Secondary | hypotension | incidence of post tourniquet hypotension | 15 minutes after start of deflation of cuff | |
Secondary | cardiac output | cardiac output after starting deflation using non invasive electrical cardiometry | 15 minutes after start of deflation of cuff |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04239066 -
Penile Ischemia for Hypospadias Repair and The Patients and Surgeons Reported Outcomes
|
N/A | |
Not yet recruiting |
NCT04277065 -
Bulldog vs. Cotton Tourniquet in Laparoscopic Hepatectomy for Patients
|
N/A | |
Recruiting |
NCT05926154 -
Evaluation of Ischemia and Reperfusion Interval With Neuromonitorization in Tourniquet Application
|
N/A | |
Completed |
NCT04307290 -
Dexmedetomidine on Tourniquet Induced -Systemic Effects
|
Phase 4 | |
Terminated |
NCT04402775 -
Brachiocephalic Arteriovenous Fistulae: Two Different Techniques of Bloodless Surgery and Their Effect on Fistula Stenosis.
|
N/A | |
Completed |
NCT02389725 -
The Effect of Two Different Tourniquet Techniques on Peripheral IV Access Success Rates
|
N/A |