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Efficacy and Safety of Gemlapodect in Adults and Adolescents With Tourette Syndrome — Allevia2  

Tourette Syndrome Clinical Trial

Official title:
A Double-blind, Placebo-controlled, Phase 2b, Multi-center, Twelve-week Prospective Study to Evaluate the Efficacy and Safety of Gemlapodect in Adult and Adolescent Patients With Tourette Syndrome

Clinical Trial Summary

This study is designed to evaluate the efficacy and safety of gemlapodect (NOE-105) on reducing tics associated with Tourette Syndrome (TS) in adults with TS. Adolescents will be enrolled after a sentinel cohort of adults is complete.

Clinical Trial Description

Gemlapodect is an investigational selective PDE10A inhibitor with a potential therapeutic effect for the treatment of tics associated with Tourette Syndrome (TS). This is a multi-center, double-blind, parallel-arm, placebo-controlled study in patients with TS. Following screening to confirm eligibility and to wash-out previous TS medication during a 14-day placebo run-in, patients will be randomized 1:1 on Day 1 to receive gemlapodect or placebo once daily for 12 weeks. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06315751
Study type Interventional
Source Noema Pharma AG
Contact Noema Pharma
Phone please contact via email
Email clinicaltrials@noemapharma.com
Status Not yet recruiting
Phase Phase 2
Start date May 31, 2024
Completion date December 31, 2026
View Details
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