Deep Brain Stimulation in Forel's H Field in Tourette's Syndrome

Status Active, not recruiting

Clinical Trial Summary

Tourette's Syndrome (TS) is a neurodevelopmental disease characterized tics that start before the age of 18 years. About 5% of cases do not respond to drug treatment and can be classified as refractory and in these cases surgical treatment, with deep brain stimulation, appears as a therapeutic possibility, but with still conflicting results. Our hypothesis is that DBS in Forel's H Field could improve tourette's symptoms, neurological and psychiatric ones.

Clinical Trial Description

Sixteen patients with TS will be included in our protocol. The tics must have a negative influence in the quality of life of these patients. Patients will be submitted to a neuronavigation protocol for the precise location of the surgical target. After the surgery all patients will have the device turned ON for 6 months. After the first 6 months participants will be randomly in two groups, one to stay with device ON or turned OFF at a period of 3 months. After that the groups will cross over for more 3 months. Clinical and video evaluations will be conducted before the surgery, at end of open fase, in the moment of cross over and at end of all. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04342754
Study type	Interventional
Source	University of Sao Paulo General Hospital
Contact
Status	Active, not recruiting
Phase	N/A
Start date	February 27, 2019
Completion date	June 27, 2023

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See also
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