Clinical Trials Logo
  1. Home
  2. Tourette's Syndrome
  3. NCT01133353

A Study of the Effectiveness and Safety of Tetrabenazine MR in Pediatric Subjects With Tourette's Syndrome — TBZ-MR  

Tourette's Syndrome Clinical Trial

Official title:
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Tetrabenazine MR in Subjects Aged 5 up to 17 Years With Tourette's Syndrome

Clinical Trial Summary

The purpose of this clinical trial is to study the therapeutic effect of tetrabenazine MR in children with Tourette's Syndrome, as measured by the improvement in total tic score of the Yale Global Tic Severity Scale (YGTSS).

Clinical Trial Description

Tourette's Syndrome (TS) is typically diagnosed in early childhood (6-7 years) or before the age of 21 years and is characterized by chronic, intermittent motor and phonic tics. There is a body of evidence, mostly from the clinical experience data, suggesting the efficacy of tetrabenazine in TS patients with tics, including patients who were unresponsive to other treatment options. These publications consistently report the usefulness of tetrabenazine as an alternative to conventional neuroleptics for the treatment of TS. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01133353
Study type Interventional
Source Bausch Health Americas, Inc.
Contact
Status Withdrawn
Phase Phase 2
Start date March 2011
Completion date December 2011
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT00965211 - Evaluation of the HBDL Coil Transcranial Magnetic Stimulation (TMS) Device - Safety and Feasibility Study for the Treatment of Tourette Syndrome N/A
Recruiting NCT00152750 - Study of Clonidine on Sleep Architecture in Children With Tourette's Syndrome (TS) and Comorbid ADHD Phase 4
Terminated NCT00226824 - Safety Study of Galantamine in Tic Disorders Phase 4
Completed NCT00241176 - Open Label Trial of Aripiprazole in Children and Adolescents With Tourette's Disorder Phase 4
Completed NCT01244633 - Ecopipam Treatment of Tourette Syndrome Phase 1/Phase 2
Recruiting NCT04805385 - Effects of Lactobacillus Plantarum PS128 in Patients With Tourette's Syndrome N/A
Completed NCT00026000 - Brain Activation in Vocal and Motor Tics N/A
Terminated NCT00001260 - Brain Tissue Collection for Neuropathological Studies
Completed NCT02102698 - Ecopipam Treatment of Tourette's Syndrome in Subjects 7-17 Years Phase 2
Withdrawn NCT02112253 - Optimising Anterior Pallidal Deep Brain Stimulation for Tourette's Syndrome Phase 1/Phase 2
Completed NCT02205918 - Brain-Behavior Interactions in Tic Suppression
Terminated NCT00282139 - Aripiprazole in the Treatment of Tourette's Syndrome N/A
Completed NCT03042507 - Psychosocial Intervention for Young Children With Chronic Tics N/A
Completed NCT01019343 - Physiological Investigations of Movement Disorders N/A
Completed NCT02619084 - Subthalamic Stimulation in Tourette's Syndrome Phase 2
Completed NCT00368433 - Hypersensitivity in Tourette Syndrome N/A
Withdrawn NCT01475383 - Study Evaluating The Safety And Efficacy Of PF-03654746 In Adult Subjects With Tourette's Syndrome Phase 2
Not yet recruiting NCT06361004 - Exploring DBS Efficacy in Treatment-refractory Tourette's Syndrome N/A
Completed NCT00139308 - High Frequency Stimulation of the GPi or Thalamus in Tourette's Syndrome Phase 1