Clinical Trials Logo

Total Knee Arthroplasty clinical trials

View clinical trials related to Total Knee Arthroplasty.

Filter by:

NCT ID: NCT04458480 Recruiting - Rehabilitation Clinical Trials

Effect of Fast Inpatient Rehabilitation After TKA

Start date: September 7, 2019
Phase:
Study type: Observational

Rehabilitation is an important part of the post-operative treatment after TKA by consensus. This study intends to analysis whether fast inpatient rehabilitation after TKA can improve knee joint or general function, and ultimately explore for effects and values of fast inpatient rehabilitation after TKA.

NCT ID: NCT04427722 Recruiting - Clinical trials for Total Knee Arthroplasty

PMCF Study of MPS-Flex® Knee System in TKA

Start date: February 25, 2021
Phase:
Study type: Observational

The objective of this study is to obtain implant survivorship and clinical outcomes data for the commercially available MPS-Flex® Total Knee Joint Prostheses used in primary total knee arthroplasty (TKA).

NCT ID: NCT04423276 Recruiting - Clinical trials for Total Knee Arthroplasty

Efficiency of Donepezil in Elderly Patients for Prevention of POCD Dysfunction

Start date: June 14, 2020
Phase: Phase 4
Study type: Interventional

Postoperative cognitive dysfunction (POCD) occurs mainly in aged patients. POCD may increase the mortality and morbidity. However, the mechanism of POCD is not clear yet and no effective therapy method was proved. According to our previous study, the central cholinergic system impaired by the anesthesia and surgery play a very important role in the POCD and donepezil an acetylcholinesterase inhibitor can prevent the POCD after isoflurane anesthesia in aged mice. Donepezil is a commercial medicine used for the Alzheimer Disease, which is tolerable and has minimal adverse events. In present study a multi-center randomized case control study was conducted and we hypothesized that donepezil attenuate the POCD.

NCT ID: NCT04308798 Recruiting - Clinical trials for Total Knee Arthroplasty

Comparison of Surgical Glove Contamination During Total Knee Arthroplasty Procedure : a Randomized Controlled Trial

Start date: July 2020
Phase: Phase 3
Study type: Interventional

Total knee arthroplasty post-op surgical site infection rate about 0.5- 5% Pre-operative , perioperative and post-operative prevention are importance for reduce surgical site infection The prevention of surgical-site infections (SSIs) is an integral component of nosocomial infection control and a major priority in orthopedic surgery. Surgical wound contamination must be prevented to avoid patient colonisation by microorganisms during surgery. Surgical glove changing perioperative can reduce contamination and perforation rate Orthopedic surgery had found contamination rate about 20-28 % Joint replacement procedure found contamination rate about 38-67% of all orthopedic surgery 12% of gloves are contaminated after draping and 24% once patient installation is complete. We hypothesis that changing surgical glove during total knee arthroplasty can reduce contamination rate on surgical glove.

NCT ID: NCT04163445 Recruiting - Knee Osteoarthritis Clinical Trials

Comparison of TKAs Using Force Plate Analysis

Start date: November 11, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate performance of two modern total knee arthroplasty designs using patient reported outcomes and force exhibited during various activities of daily living.

NCT ID: NCT03915522 Recruiting - Knee Osteoarthritis Clinical Trials

Adductor Canal Block in an Enhanced Recovery Program After Total Knee Arthroplasty

Start date: May 14, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effectivity of adductor canal block performed the day after total knee arthroplasty surgery in reducing pain and improving walking ambulation ability and muscle strength.

NCT ID: NCT03877042 Recruiting - Clinical trials for Total Knee Arthroplasty

The Efficacy of Using CR and PS Prosthesis in Total Knee Replacement

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

The investigators will investigate the efficacy of using CR and PS implants in TKA. The investigators will conduct TKA with different implants simultaneously on one patient to compare the post-operation efficacy of both implants.

NCT ID: NCT03692858 Recruiting - Clinical trials for Total Knee Arthroplasty

IPACK Block in Total Knee Arthroplasty

Start date: October 1, 2018
Phase: Phase 2
Study type: Interventional

100 patients ASA I-III, undergoing total knee arthroplasty under spinal anesthesia, will be randomly assigned into one of two groups, namely group A (n=50), where an adductor canal block and an IPACK block will be performed preoperatively and group B (n=50) where an adductor canal block only will be performed preoperatively. All patients will receive a standardized multimodal approach, including pregabalin, paracetamol, and PCA with morphine. NRS scores in static and dynamic conditions during the first 48 hours postoperatively, morphine consumption during the first 24 hours postoperatively will be measured and additionally, patient satisfaction, complications, range of knee motion, moblization, functionality, delirium ocurence will be recorded. Chronic pain will be assessed in 3 and 6 months postoperatively.

NCT ID: NCT03607461 Recruiting - Clinical trials for Total Knee Arthroplasty

Using a Smartphone App to Aid in Functional Mobility Return Following Total Knee Arthroplasty

Start date: July 2018
Phase: N/A
Study type: Interventional

Traditional home health care for individuals recovering from unilateral TKA is expensive and provides a higher level of service than most individuals, aged 45 to 64, require. Use of smartphone technology has the potential to drive down costs while maintaining outcomes for this patient population. The proposed randomized controlled trial would determine the efficacy and proper dose-response of a smartphone app to reduce costs and maintain outcomes for the desired patient population compared to traditional home care.

NCT ID: NCT03566875 Recruiting - Clinical trials for Total Knee Arthroplasty

Total Knee Arthroplasty Robot Assisted With MAKO™ Robotic System Compared to the Conventional Total Knee Arthroplasty by Mechanical Ancillary

TKA-MAKO
Start date: April 23, 2018
Phase: N/A
Study type: Interventional

For the total knee arthrorplasty (TKA), the placement of a prosthesis is delicate and the correct positioning of the implants determines the result of the surgery. Navigation has improved surgical accuracy but remains inadequate with nearly 20% malposition. In the early 2010s, robot-assisted surgery solutions were born. Amongst its offers, Stryker's MAKO™ system appears to be the most advanced and developed due to its precision and its flexibility of use during surgery. In this study, the investigators evaluate the placement of the total knee prosthesis with the MAKO™ system compared to the placement of the total knee prosthesis with a conventional mechanical system for TKA