Tooth Loss Clinical Trial
Official title:
A Pilot RCT Study Comparing Dimensional Alterations After Socket Grafting With Xenograft Versus Allograft
To compare dimensional changes in extraction socket of single rooted teeth, 6 months post extraction, when grafted with xenograft versus allograft.
AIM To compare dimensional changes in extraction socket of single rooted teeth, 6 months post extraction, when grafted with xenograft versus allograft. PRIMARY OBJECTIVE Horizontal and vertical dimensional changes of extraction sockets as evaluated in a CBCT scan immediately post extraction and 6 months post extraction when grafted with xenograft versus allograft. SECONDARY OBJECTIVE 1. Difference in horizontal dimensional changes in xenograft and allograft groups as measured intra-operatively after extraction and at re- entry 6 months post extraction. 2. Difference in vertical dimensional changes in xenograft and allograft groups as measured intra-operatively after extraction and at re- entry 6 months post extraction. 3. Difference in histologic analysis of bone biopsy cores taken in xenograft and allograft groups at 6 months re-entry from osteotomy site. Difference in newly regenerated supracrestal bone height and volume will be measured directly from the segmented images from MicroCT. NULL HYPOTHESIS There is no difference between the two groups for any of the parameters evaluated. ;
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