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Tooth Loss clinical trials

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NCT ID: NCT03645356 Completed - Clinical trials for Malocclusion, Angle Class I

Comparison Between Clear Aligners and Traditional Fixed Appliances in the Treatment of Four-premolar-extraction Cases

Start date: August 19, 2018
Phase: N/A
Study type: Interventional

Patients who have severe crowding that require four premolars extraction will be treated in this study. The efficacy of the clear aligners and vestibular fixed appliances will be assessed. The treatment result of these two different methods will be explored using the Peer Assessment Rating (PAR) in two different times (T0: Before treatment, T1: After treatment) and the American Board of Orthodontics Objective Grading System (ABO-OGS) after treatment (T1). There are two groups: First group (Experimental): the patients in this group will be treated using clear aligners. Second group (Control): the patients in this group will be treated using fixed appliances.

NCT ID: NCT03538184 Completed - Tooth Loss Clinical Trials

Molecular Content of Peri-implant Sulcus During Wound Healing and Osseointegration Following Drilling and Piezosurgery

Start date: May 2013
Phase: N/A
Study type: Interventional

This study aims to evaluate the levels of cytokines, chemokines and growth factors in peri-implant sulcular fluid (PISF) during healing and osseointegration at osteotomy sites prepared either with piezosurgery (PS) or drills (D). Fourteen patients having bilateral partial edentulism in the posterior maxilla were enrolled and 38 osteotomies were prepared. Implants were placed with one-stage surgery. Insertion torque, early healing index, probing depth and modified gingival and plaque indices and crestal bone (CB) loss were measured. PISF was collected from 4 sites from each implant at weeks 2, 4, 8, 12 and 24. PISF samples were analysed by a 30-Plex immunoassay. Effect of time and osteotomy method on molecules employed Brunner-Langer method.

NCT ID: NCT03471000 Completed - Tooth Loss Clinical Trials

The Influence of the Crown-implant Ratio on the Crestal Bone Level and Implant Secondary Stability

Start date: January 1, 2012
Phase: N/A
Study type: Interventional

The aim of the study was to determine whether implant length and the crown-to-implant (C/I) ratio influence implant stability and the loss of the surrounding marginal bone, and whether short implants can be used instead of sinus augmentation procedures.

NCT ID: NCT03410251 Completed - Tooth Loss Clinical Trials

Long- Term Follow-up of Extraction Socket Management

Start date: June 2016
Phase: N/A
Study type: Observational

Twenty-nine patients needing single tooth replacement in aesthetic area were treated by extraction and socket preservation with saddle connective tissue graft between September 2009 and February 2012. Computed Tomography scan were taken at baseline just after the surgery and 3 months later. Long- term evaluation of this particular socket management procedure was evaluated by recalling successfully seventeen of theses patients in June 2016. At this time, a clinical and radiographical consultation was done and Cone Beam CT was taken. Horizontal and vertical bone dimensional changes were then assessed thanks to 3D imaging analysis and esthetic and implants outcomes were evaluated.

NCT ID: NCT03331185 Completed - Alveolar Bone Loss Clinical Trials

Changes of Soft and Hard Tissues After Alveolar Ridge Preservation: Freeze-dried Bone Allograft vs. L-PRF Clot

Start date: January 3, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

A Clinical Trial to study the effectiveness between two, tooth socket grafting materials namely, Freeze Dried Bone Allograft (human derived bone particles) and Leukocytic-Platelet Rich Fibrin (the patient's own centrifuged blood). The purpose of this study is to compare the effects (good and bad) of Bone Allograft to Platelet Rich Fibrin to see which material would be the most effective in maintaining the volume of the gum and bone of the jaw during the healing phase as well as minimizing the amount of pain and/or swelling following tooth extraction.

NCT ID: NCT03302143 Completed - Missing Tooth Clinical Trials

Radiographic and the Esthetic Outcome of Two Different Bone Grafting Techniques in Early Implant Placement

Start date: July 30, 2013
Phase: N/A
Study type: Interventional

Total of 48 subjects were randomly assigned to treatment groups: UT Health Science Center at San Antonio Chi Mei Medical Center, Tainan, Taiwan Patients require a maxillary non-molar extraction site that is planned to be replaced by a dental implant and crown. This includes Straumann BL SLActive: Narrow (3.3mm) & Regular (4.1mm) Crossfit implants in all available lengths. Patients were randomly selected to receive either FDBA (test) or Autogenous bone + DBBM (control/standard) for contour augmentation.

NCT ID: NCT03234868 Completed - Tooth Loss Clinical Trials

Benefit of the Digital Workflow for Screw-retained Single Implant Restorations

Start date: January 1, 2016
Phase: Phase 4
Study type: Interventional

The aim of this research project is emphasize the benefit of the digital workflow compared to conventional impressions and crown processing with standard la procedures. The objectives of the present study are to measure and compare the global cost, the time spent in the dental chair and in the lab and the fit of both digital and conventional workflow. Additionally, patient centered outcomes will be recorded.

NCT ID: NCT03198520 Completed - Missing Teeth Clinical Trials

REFRAME RPD Post-Market Clinical Study

Start date: June 6, 2017
Phase: N/A
Study type: Interventional

To evaluate the change in patient Oral Health-related Quality of Life (OHRQoL) from wearing a cobalt chrome (CoCr) removable partial denture (RPD) to wearing the Solvay Dental 360TM polymer Removable Partial Denture (RPD) for 8 weeks.

NCT ID: NCT03136913 Completed - Clinical trials for Loss of Teeth Due to Extraction

A Comparison Between Primary and Secondary Flap Coverage in Extraction Sites: A Pilot Study

Start date: February 17, 2015
Phase: N/A
Study type: Interventional

This study is being conducted to compare the outcomes of two separate surgical techniques used in tooth extraction and ridge preservation. Ridge preservation is done to potentially minimize the amount of bone loss that occurs between the tooth extraction and implant or bridge placement, as compared to leaving the extraction site empty. There are two techniques that are commonly used for these procedures, either to close the surgical site of the extracted tooth with sutures (closed flap technique) or to leave the extraction site open to heal naturally (open flap technique). In the open flap technique there will be sutures used to secure and hold down the material used to cover the wound, called a non-resorbable membrane. The flaps will remain in their natural position, the site will fill up naturally with new tissue from the bottom up and then close itself in from the sides. The investigators want to see which technique offers better healing and reduces bone loss.

NCT ID: NCT03076138 Completed - Bone Loss Clinical Trials

Gene-activated Bone Substitute for Maxillofacial Bone Regeneration

Start date: March 6, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the gene-activated bone substitute consisting of octacalcium phosphate and plasmid DNA encoding vascular endothelial growth factor (VEGF) for maxillofacial bone regeneration. The patients with congenital and acquired maxillofacial bone defects and alveolar ridge atrophy will be enrolled.