Clinical Trials Logo
  1. Home
  2. Tooth Diseases
  3. NCT02801552

Regenerative Endodontic Procedure of Immature Permanent Teeth With Apical Periodontitis Using PRF

Tooth Diseases Clinical Trial

Official title:
Regenerative Endodontic Procedure of Immature Permanent Teeth With Apical Periodontitis Using Platelet-rich Fibrin : A Pilot Randomized Controlled Trial

Clinical Trial Summary

This study evaluates the clinical effect of regenerative endodontic procedure using PRF in immature permanent teeth with apical periodontitis. Half of participants will receive the PRF instead of blood clots in the regenerative endodontic procedure, while the other half will receive a blood clots in the regenerative endodontic procedure.

Clinical Trial Description

The conventional method of regenerative endodontic procedure using a blood clot as scaffold materials has shown successful results. However, it is very difficult to induce bleeding and place mineral trioxide aggregate over a blood clot. Platelet-rich fibrin (PRF), a second-generation platelet concentrate. PRF is a matrix of autologous fibrin containing a large quantity of platelets, growth factors and leukocytes. PRF preparation technique is very simple, inexpensive and doesn't require any chemical agents. The purpose of this study is to test the hypothesis that the use of PRF in regenerative endodontic procedure of immature permanent teeth with apical periodontitis will accelerate periapical bone healing and stimulate the root maturation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02801552
Study type Interventional
Source Fujian Medical University
Contact
Status Completed
Phase N/A
Start date May 2016
Completion date February 2020
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT05792800 - Dental Practitioners KAP Regarding Caries Preventive Measures in Cairo and Riyadah
Not yet recruiting NCT05792215 - KAP of Dental Practitioners Regarding CRA
Terminated NCT03871569 - Medico-economical Evaluation on Buccodental Teleexpertise in Nursing Home N/A
Active, not recruiting NCT04324008 - Clinical Comparison of Different Flowable Resin Composites N/A
Completed NCT06112366 - Comparison of Silk Suture and Tissue Adhesive for Wound Closure After Impacted Tooth N/A
Recruiting NCT04033380 - Clinical Efficacy of Ceramic vs Resin Block Endocrown N/A
Completed NCT04003493 - LifE Style, Nutrition and Oral Health in Care Givers (LENTO) N/A
Completed NCT03708510 - Clinical Evaluation of Two Low-shrinkage Composites N/A
Completed NCT06067542 - Effects of Chlorhexidine Toothpaste on Wound Healing After Impacted Tooth Extraction N/A
Completed NCT03556553 - Clinical Evaluation of a Self-Adhering Flowable Composite in Class I Cavities N/A
Completed NCT04291443 - Proteomics and Orthodontic Root Resorption N/A
Completed NCT03553966 - Hydroxyapatite-toothpaste and Enamel Caries in the Primary Dentition N/A
Recruiting NCT01805869 - Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal
Completed NCT04385693 - Intentional Pulpotomy to Preserve Hopeless Molars N/A
Completed NCT02429947 - An Analysis of the Symptomatic Domains Most Relevant to Charcot Marie Tooth Neuropathy (CMT) Patients N/A
Recruiting NCT04029324 - Clinical Outcomes of Immediate Implant Placement and Early Implant Placement N/A
Recruiting NCT06212232 - A New Piezoelectric Technique in Third Molar Surgery N/A
Completed NCT04827693 - The Cortical Shield for Facial Bone Reconstruction
Completed NCT02868957 - Repetition Improves Precision and Trueness of Digital Intraoral Scans N/A
Completed NCT06280014 - Evaluation of the Effects of Mefenamic Acid and Dexketoprofen on Postoperative Wisdom Dental Surgery N/A