Periapical Periodontitis Clinical Trial
Official title:
Regenerative Endodontic Procedure of Immature Permanent Teeth With Apical Periodontitis Using Platelet-rich Fibrin : A Pilot Randomized Controlled Trial
This study evaluates the clinical effect of regenerative endodontic procedure using PRF in immature permanent teeth with apical periodontitis. Half of participants will receive the PRF instead of blood clots in the regenerative endodontic procedure, while the other half will receive a blood clots in the regenerative endodontic procedure.
The conventional method of regenerative endodontic procedure using a blood clot as scaffold materials has shown successful results. However, it is very difficult to induce bleeding and place mineral trioxide aggregate over a blood clot. Platelet-rich fibrin (PRF), a second-generation platelet concentrate. PRF is a matrix of autologous fibrin containing a large quantity of platelets, growth factors and leukocytes. PRF preparation technique is very simple, inexpensive and doesn't require any chemical agents. The purpose of this study is to test the hypothesis that the use of PRF in regenerative endodontic procedure of immature permanent teeth with apical periodontitis will accelerate periapical bone healing and stimulate the root maturation. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03102879 -
Encapsulated Mesenchymal Stem Cells for Dental Pulp Regeneration.
|
N/A | |
Completed |
NCT00226148 -
Immediate Implant Placement in the Molar Regions
|
Phase 0 | |
Completed |
NCT05718596 -
Quantitative Assessment of the Efficacy of Sweeps Laser Activation Systems
|
N/A | |
Recruiting |
NCT00762840 -
Safety and Efficacy of the Apexum Ablator
|
N/A | |
Recruiting |
NCT05525013 -
Effect of Simvastatin Versus Calcium Hydroxide Intracanal Medications on Post-operative Pain and Interleukin 6 and 8
|
N/A | |
Active, not recruiting |
NCT05555043 -
Comparison of Clinical Outcomes Between GentleWave® and Biolase®
|
N/A | |
Recruiting |
NCT06322979 -
Premixed Bioceramic Putty as an Apical Plug in Immature Anterior Permanent Teeth
|
N/A | |
Completed |
NCT02947763 -
Single Versus Multiple Visits Endodontic Treatment
|
Phase 1 | |
Completed |
NCT05857436 -
Relationship Apical Periodontitis and the Main Bacterial Species in the Oral Microbiota
|
N/A | |
Active, not recruiting |
NCT03660163 -
Assessment of the Outcome of Endodontic Treatment Using Cone Beam Computed Tomography.
|
||
Completed |
NCT02632513 -
Effect of Passive Ultrasonic Irrigation on Success of Primary Endodontic Treatment
|
N/A | |
Completed |
NCT01312194 -
Periapical Healing After One or Two-visits to Endodontic Treatment in Adolescents Patients
|
N/A | |
Completed |
NCT00223327 -
Measurement of Bite Force in Humans
|
Phase 0 | |
Completed |
NCT05297747 -
Adrenomedullin Upregulation in Apical Periodontitis
|
N/A | |
Completed |
NCT03708081 -
Comparative Evaluation of Different File Systems in Postoperative Pain
|
||
Recruiting |
NCT01799187 -
Research of Revascularization in Immature Teeth With Periapical Periodontitis
|
N/A | |
Completed |
NCT06023901 -
The Importance of Prostaglandin and Nitric Oxide Synthesis in Apical Periodontitis
|
N/A | |
Completed |
NCT02747082 -
Antibacterial Effectiveness of Two Root Canal Irrigants
|
Phase 2 | |
Completed |
NCT06339905 -
The Effects of EndoActivator on Postoperative Pain and Root Canal Treatment Success
|
N/A | |
Completed |
NCT05719987 -
Biodentine as an Apical Plug in Immature Permanent Molars
|
N/A |