Clinical Trials Logo
  1. Home
  2. Tonsillitis
  3. NCT00136877
  4. Details
NCT00136877 Clinical Trial

Tonsillectomy in Recurrent Tonsillitis

Tonsillitis Clinical Trial

Official title:
Effect of Tonsillectomy on Preventing Recurrent Streptococcal Throat Infections: A Randomized Controlled Trial

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT00136877
Other study ID # Diary nro 135/2001
Secondary ID
Status Active, not recruiting
Phase N/A
First received August 26, 2005
Last updated December 27, 2006
Start date October 2001
Est. completion date December 2005

Study information
Verified date December 2006
Source Oulu University Hospital
Contact n/a
Is FDA regulated No
Health authority Finland: Finnish Medicines Agency
Study type Interventional

Clinical Trial Summary

The purpose of this study is to determine whether tonsillectomy is effective in preventing further streptococcal pharyngitis episodes in patients with recurrent tonsillitis.

Description:

Tonsillectomy is widely used worldwide in recurrent streptococcal tonsillitis, but its effect remains unknown.

In this randomized controlled trial, the effect of tonsillectomy (compared to watchful waiting) in preventing further culture proven symptomatic streptococcal pharyngitis episodes is studied. In addition, symptoms after the operation, side effects, and life quality issues are recorded.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 70
Est. completion date December 2005
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 14 Years and older
Eligibility Inclusion Criteria:

- At least 3 tonsillitis episodes during the preceding year (at least one verified by culture or antigen testing)

Exclusion Criteria:

- Other serious illness

- Long term antibiotic treatment for other disease

- Documented immunologic disorder

- Pregnancy

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Procedure:
• (adeno)tonsillectomy

Locations
Country Name City State
Finland Oulu University Hospital Oulu

Sponsors (1)
Lead Sponsor Collaborator
Oulu University Hospital

Country where clinical trial is conducted

Finland, 

Outcome
Type Measure Description Time frame Safety issue
Primary microbiologically confirmed streptococcal pharyngitis episodes
Secondary side effects
Secondary symptoms
Secondary quality of life issues
See also
  Status Clinical Trial Phase
Recruiting NCT04083417 - Sore Throat in Primary Care - a Comparison of Phenoxymethylpenicillin and no Antibiotic Treatment Phase 4
Completed NCT04551196 - Management of Post-Tonsillectomy Pain in Pediatric Patients Phase 3
Active, not recruiting NCT03654742 - Intracapsular Tonsillectomy in Adults N/A
Completed NCT04016051 - Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infections Phase 3
Completed NCT02712307 - Study of 5 and 10 Days Treatment With Penicillin Against Sore Throat Caused by Streptococci Phase 4
Enrolling by invitation NCT02205580 - Continuous Intravenous Sufentanil Infusion for Postoperative Pain Management Following Tonsillectomy or Adeno-tonsillectomy in Children Phase 4
Completed NCT01721486 - Acetaminophen's Efficacy For Post-operative Pain Phase 4
Active, not recruiting NCT01691690 - Analgesic Effect of IV Acetaminophen in Tonsillectomies Phase 2
Completed NCT00393744 - Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children Phase 3
Completed NCT00095368 - APC-111 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) for 10 Days in Patients With Strep Throat Phase 3
Recruiting NCT04646525 - The Relationship Between Covid-19 Infection in Pediatric Patients and Secondary Lymphoid Organs
Completed NCT01361399 - Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common Cold Phase 3
Recruiting NCT03137823 - Diagnosis of GABHS Tonsillitis - Comparison Between Culture From Tonsills and Culture From the Bucal Surface N/A
Completed NCT02571075 - Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea N/A
Completed NCT00547391 - Recurrent Throat Infections and Tonsillectomy Phase 4
Completed NCT00242281 - APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat Phase 3
Completed NCT01465009 - Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Throat Associated With a Common Cold Phase 4
Recruiting NCT04164511 - Does Ice Cream Help With Post-tonsillectomy Pain
Completed NCT04653376 - Relationship of Endoplasmic Reticulum Stress and Tonsillar Tissue Diseases
Recruiting NCT06326983 - Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery N/A