Tonsillectomy in Recurrent Tonsillitis

Status Active, not recruiting

Clinical Trial Summary

The purpose of this study is to determine whether tonsillectomy is effective in preventing further streptococcal pharyngitis episodes in patients with recurrent tonsillitis.

Clinical Trial Description

Tonsillectomy is widely used worldwide in recurrent streptococcal tonsillitis, but its effect remains unknown.

In this randomized controlled trial, the effect of tonsillectomy (compared to watchful waiting) in preventing further culture proven symptomatic streptococcal pharyngitis episodes is studied. In addition, symptoms after the operation, side effects, and life quality issues are recorded. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Tonsillitis

Clinical Trial Details

NCT number	NCT00136877
Study type	Interventional
Source	Oulu University Hospital
Contact
Status	Active, not recruiting
Phase	N/A
Start date	October 2001
Completion date	December 2005

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04083417` - Sore Throat in Primary Care - a Comparison of Phenoxymethylpenicillin and no Antibiotic Treatment	Phase 4
Completed	`NCT04551196` - Management of Post-Tonsillectomy Pain in Pediatric Patients	Phase 3
Active, not recruiting	`NCT03654742` - Intracapsular Tonsillectomy in Adults	N/A
Completed	`NCT04016051` - Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infections	Phase 3
Completed	`NCT02712307` - Study of 5 and 10 Days Treatment With Penicillin Against Sore Throat Caused by Streptococci	Phase 4
Enrolling by invitation	`NCT02205580` - Continuous Intravenous Sufentanil Infusion for Postoperative Pain Management Following Tonsillectomy or Adeno-tonsillectomy in Children	Phase 4
Completed	`NCT01721486` - Acetaminophen's Efficacy For Post-operative Pain	Phase 4
Active, not recruiting	`NCT01691690` - Analgesic Effect of IV Acetaminophen in Tonsillectomies	Phase 2
Completed	`NCT00393744` - Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children	Phase 3
Completed	`NCT00095368` - APC-111 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) for 10 Days in Patients With Strep Throat	Phase 3
Recruiting	`NCT04646525` - The Relationship Between Covid-19 Infection in Pediatric Patients and Secondary Lymphoid Organs
Completed	`NCT01361399` - Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common Cold	Phase 3
Recruiting	`NCT03137823` - Diagnosis of GABHS Tonsillitis - Comparison Between Culture From Tonsills and Culture From the Bucal Surface	N/A
Completed	`NCT02571075` - Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea	N/A
Completed	`NCT00547391` - Recurrent Throat Infections and Tonsillectomy	Phase 4
Completed	`NCT00242281` - APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat	Phase 3
Completed	`NCT01465009` - Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Throat Associated With a Common Cold	Phase 4
Recruiting	`NCT04164511` - Does Ice Cream Help With Post-tonsillectomy Pain
Completed	`NCT04653376` - Relationship of Endoplasmic Reticulum Stress and Tonsillar Tissue Diseases
Recruiting	`NCT05656365` - Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders