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Tobacco Use Disorder clinical trials

View clinical trials related to Tobacco Use Disorder.

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NCT ID: NCT01337817 Completed - Smoking Clinical Trials

A Pilot Study to Evaluate the Efficacy and Safety of Ariva® Silver Wintergreen in Healthy Smokers

Start date: September 2009
Phase: Phase 1
Study type: Interventional

Study to determine the safety and effectiveness of silver salt in Ariva® Silver Wintergreen Lozenge on discouraging smoking, by its imparting an unfavorable taste to the smoker when tobacco is smoked.

NCT ID: NCT01336816 Completed - Smoking Clinical Trials

A Pilot Study to Evaluate the Efficacy of Ariva® Silver Wintergreen, a Smoking Aversive Lozenge

Start date: July 2009
Phase: Phase 1
Study type: Interventional

This is a study to determine the safety and effectiveness of silver salt in Ariva® Silver Wintergreen Lozenge on discouraging smoking, by its imparting an unfavorable taste to the smoker when tobacco is smoked.

NCT ID: NCT01334736 Completed - Tobacco Dependence Clinical Trials

A Study of Novel Smoking Cessation Interventions in Current and Former Injection Drug Users

Start date: April 2011
Phase: N/A
Study type: Interventional

Cigarette smoking is very common in current and former injection drug users and is known to cause chronic lung diseases. Quitting smoking is proven to improve the health of people addicted to cigarettes. . Little information exists regarding the perceptions and characteristics of drug users regarding quitting smoking. Additionally, most programs designed to help people quit smoking are not very successful. One reason these programs may not work well is because it is difficult to motivate people to quit smoking. New methods of motivating changes in behavior include small monetary payments for healthy behavior and reporting breathing tests with the concept of "lung age," which is the age of an average healthy person with similar breathing test results. For example, a health care provider can report results as "Although you are 50 years old, you have the lungs for a 70 year old". In this proposal, the investigators plan to first explore the beliefs and characteristics of current and former injection drug users and how they are related to quitting smoking. The investigators then plan to study whether the use of two new methods of motivation increases the chances that this group will stop smoking.

NCT ID: NCT01333202 Completed - Clinical trials for Tobacco Use Disorder

Fresh Lime Alone for Smoking Cessation

LIM
Start date: March 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether fresh lime alone is effective for smoking cessation.

NCT ID: NCT01330030 Completed - Clinical trials for Tobacco Use Disorder

Selegiline Patch for Treatment of Nicotine Dependence

Start date: July 2005
Phase: Phase 2
Study type: Interventional

Relapse to smoking is a common problem affecting smokers who seek treatment. The purpose of this study is examine whether selegiline, given in the form of a skin patch, is effective in stopping smoking.

NCT ID: NCT01329614 Completed - Clinical trials for Tobacco Use Disorder

Effects of Nicotine Replacement and Repeated Cue Exposure on Cigarette Craving

Start date: October 2009
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to determine whether Cue Extinction Training will reduce relapse rates in cigarette smokers using the patch to quit.

NCT ID: NCT01328431 Completed - Smoking Cessation Clinical Trials

Treating Low-Income Smokers in the Hospital Emergency Department

Start date: October 2010
Phase: N/A
Study type: Interventional

This study will test the effectiveness of an Emergency Department (ED) initiated tobacco intervention which includes counseling and medication. Our proposed intervention combines a Brief Negotiated Interview (BNI) with initiation of nicotine patch and gum in the ED, as well as a faxed referral to the state's Smokers' Quitline. A 6 week supply of nicotine patches and nicotine gum are provided to subjects in the intervention arm. Subjects randomized to the control arm will receive a brochure from the state's Smokers' Quitline only. The primary hypothesis is that the intervention will be superior to the control condition in reducing self-reported and biochemically verified 7-day tobacco abstinence at 3 months.

NCT ID: NCT01323725 Completed - Clinical trials for Tobacco Use Disorder

Team-based Financial Incentives for Smoking Cessation

StPaulKorea
Start date: January 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to identify the effectiveness of team-base financial incentives for increasing long-term smoking cessation among employees at St. Paul's Hospital, Korea.

NCT ID: NCT01314001 Completed - Nicotine Addiction Clinical Trials

Pharmacogenetics of Nicotine Addiction Treatment

Start date: December 2010
Phase: Phase 3
Study type: Interventional

The purpose of this research program is to understand how a biomarker called the "nicotine metabolite ratio" (also referred to as NMR) may influence a smoker's ability to quit smoking.

NCT ID: NCT01308736 Completed - Clinical trials for Tobacco Use Disorder

Varenicline-Aided Cigarette Reduction in Smokers Not Ready to Quit

Start date: January 2011
Phase: N/A
Study type: Interventional

The investigators will randomize smokers to receive 1) Varenicline + smoking cessation/reduction counseling or 2) Placebo pill + smoking cessation/reduction counseling. Neither the participants nor the research therapists/evaluators will know to which condition (active or placebo pill) the participants have been assigned i.e., a double-blind study). The medication and weekly counseling will occur for 28 days. Participants will complete assessment measures just before the start of treatment (baseline), at the end-of-treatment, at 1-month, 3-month, and at 6-months to determine if there are differences in tobacco use between treatment groups.