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Tissue Perfusion clinical trials

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NCT ID: NCT05104528 Completed - Volume Overload Clinical Trials

Non-Invasive Cardiometry and Ultrasound Guided Inferior Vena Cava Collapsibility Index in Assessing Fluid Responsiveness

Start date: September 6, 2021
Phase: N/A
Study type: Interventional

43 patients between 18-60 years presenting with criteria of sepsis (life-threatening organ dysfunction caused by a dysregulated host response to infection, suspected or documented infection and an acute increase ≥2 SOFA [Sequential Organ Failure Assessment] points) will be enrolled in our study. Approval of the ethical committee and informed written consent from first degree relatives will be issued. They will be given a full and detailed explanation of the intended study protocol and will be informed about the potential benefits of the development of a successful technique as well as the potential side-effects. To compare the efficacy of non-invasive cardiometry and ultrasound (US) guided inferior vena cava (IVC) collapsibility when assessing the response of septic patients to fluid therapy guidelines of The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3); in the first six hours of ICU admission .

NCT ID: NCT05045365 Recruiting - Clinical trials for Peripheral Arterial Disease

Perfusion Assessment Using BOLD MRI and PBV in Endovascular Treatment of Peripheral Arterial Occlusive Disease

Start date: December 1, 2020
Phase:
Study type: Observational [Patient Registry]

Current assessment of lower limb ischemia cannot reflect the location and degree of ischemia. Tissue perfusion assessment was used in the diagnosis and treatment of lower limb ischemia in this project, and the quantitative evaluation of ischemia degree was realized by using its advantages of quantitative analysis and perfusion imaging.

NCT ID: NCT04764591 Completed - Regional Anesthesia Clinical Trials

Tissue Perfusion for Different Approaches of Brachial Plexus Block

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

To compare the two different approaches of infraclavicular brachial plexus block in forearm, wrist and hand surgery in terms of perfusion index, tissue oxygenation, sensory and motor block onset time and total effect time, first analgesic time, side effects and complications, and duration of block application.

NCT ID: NCT04230603 Recruiting - Inflammation Clinical Trials

Tissue Characterization With Hyperspectral Imaging (HSI)

HSIT
Start date: June 6, 2019
Phase: N/A
Study type: Interventional

Hyperspectral Imaging (HSI) is a contact free method to analyse the from the tissue reflected light in the range of 500-1000nm. Aim of the study is to identify special reflex patterns to identify special tissue

NCT ID: NCT03809065 Completed - Tissue Perfusion Clinical Trials

Effects of Nitroglycerin Versus Labetalol on Tissue Perfusion During Deliberate Hypotension

Start date: January 19, 2019
Phase: Phase 4
Study type: Interventional

Deliberate hypotension is used to provide bloodless field during endoscopic sinus surgery; however, hypotension might impair perfusion of vital organs. The aim of this work is to compare the impact of nitroglycerin and labetalol on peripheral perfusion when used for induction of deliberate hypotension

NCT ID: NCT03483623 Completed - Tissue Perfusion Clinical Trials

NATO Litter: Fluid Immersion System (FIS) Versus Traditional Mattress for Pressure Dispersion

Start date: March 21, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to measure peak skin interface pressures and the total area of the body exposed to skin interface pressure above 30 mm Hg at different areas of the body in the supine position on two different support surfaces applied to a standard North Atlantic Treaty Organization (NATO) litter (NSN: 6530-01-380-7309) and a Raven 90C Litter (NSN6530-01-432-5114). The support surfaces are the Warrior Evacuation Litter Pad (WELP) and the Dolphin Fluid Immersion Simulation Stretcher System (FIS). These pressure measurements and transcutaneous oxygenation readings will allow us to determine differences between support surfaces.

NCT ID: NCT01105078 Recruiting - Tissue Perfusion Clinical Trials

Optimal Flow Rate During Cardiopulmonary Bypass

Start date: May 2010
Phase: N/A
Study type: Interventional

Regardless of the development of cardiac surgery techniques and technologies, the question of an optimal extracorporeal circulation is still unanswered. There are globally accepted standards of perfusion, however, keep many of these procedures was not evidence-based review. Generally accepted are flow rates during cardiopulmonary bypasses of 2.5 L/min/m2. This target was derived from the physiological conditions, but they are not the result of an adapted adjustment to the fundamentally non-physiological processes during extracorporeal circulation. Among other things, an increased metabolic demand during re-perfusion is not taken into account. An increasing and optimizing of the standard flow rate of 0.5 L/min/m2 should be the aim of this investigation. Under optimal perfusion, the investigators are maintaining the microcirculation and organ protection in receipt of endothelial function and oxygen transport.