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Tissue and Organ Procurement clinical trials

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NCT ID: NCT05041023 Active, not recruiting - Clinical trials for Tissue and Organ Procurement

Experience of Relatives and Intensive Care Units Caregivers of Controlled Donation After Circulatory Death

CARE-M3
Start date: October 27, 2021
Phase:
Study type: Observational

Controlled donation after circulatory death (cDCD) refers to organ donation (OD) from patients whose death is defined using circulatory criteria and from whom circulatory death occurs after a planned withdrawal of life-sustaining therapies (WLST) in intensive care units (ICUs). During cDCD, the patient is still alive while OD process is being discussed and organized. Caregivers can be particularly uncomfortable in this scenario. In the specific context of cDCD, developing knowledge on the perceptions and experiences of relatives and ICU caregivers regarding OD is crucial but remains poorly investigated. Investigators propose to conduct a prospective multicentric observational research to better understand relatives' and ICU caregivers' experience of cDCD. Better understanding their perceptions and experiences will enable to develop interventions to support and guide them throughout this practice.

NCT ID: NCT04131140 Completed - Decision Making Clinical Trials

Organ Donation and End-of-life Decisions

Start date: January 1, 2014
Phase:
Study type: Observational [Patient Registry]

Variation in organ donation after brain death (DBD) per million population varies markedly between countries, within country regions, between and within intensive care units (ICU). These circumstances also apply to end-of-life decisions in the ICU. The investigators studied all ICU deaths in Sweden between 2014-2017 in ICUs that, as routine, registered treatment plan (no treatment limitation and/or treatment limitation) and DBD. The investigators hypothesized that ICUs with high proportion of treatment limitation (withholding or withdrawing life sustaining treatment) also had less proportion of DBD.

NCT ID: NCT04123275 Completed - Clinical trials for Tissue and Organ Procurement

Prediction on Time to Death in Potential Controlled Donation After Circulatory Death (cDCD) Donors (DCD III Study)

DCDIII
Start date: July 7, 2015
Phase:
Study type: Observational

A considerable number of potential cDCD donors do not convert into actual organ donors because circulatory arrest does not occur within the predefined timeframe of warm ischemia after withdrawal of life-sustaining treatment. The main objective of this study is to determine parameters predicting time to death in potential cDCD patients.

NCT ID: NCT03458052 Recruiting - Clinical trials for Lung Transplantation

Organ Donation Survey Among Health Care Professionals in Argentina

Start date: February 16, 2018
Phase: N/A
Study type: Observational

The aim of this study is to gather information about knowledge, professional experience and attitude toward organ donation among health care professionals involved in the care of potential donors about the procurement process and potential lung donor management nationwide.

NCT ID: NCT02585921 Terminated - Adolescent Behavior Clinical Trials

Organ Donation Interventions Among High Students

Start date: October 2015
Phase: N/A
Study type: Interventional

The number of persons actively waiting on the national solid organ waiting list continues to rise while the number donating organs has failed to keep pace. This is a particular problem for some portions of northeastern Ohio where the donation rate is as low as 32%. Adolescents are an important group for organ donation efforts as they have not yet applied for a driver's license and represent the majority of future donors. Yet many organ donation interventions have not targeted adolescents. The investigators propose to utilize existing high school teen summits developed by our Consortium partners to evaluate the effectiveness of existing donation interventions. Together, the investigators will conduct a randomized controlled 2x2 factorial trial to evaluate the independent and combined effects of two donor education interventions on consent for organ donation on the electronic Ohio Donor Registry. One thousand six hundred students over the age of 15.5 years from Cleveland-area high schools will be enrolled.

NCT ID: NCT02430961 Not yet recruiting - Clinical trials for Tissue and Organ Procurement

Predictors of Apnea and Prediction of Time to Death in Donation After Cardiac Death

Start date: June 2015
Phase: N/A
Study type: Observational

Donation after Cardiac Death (DCD) is an increasingly common mechanism through wish patients can donate tissue and organs following death after withdrawal of life sustaining therapies (WLST). Unfortunately many potential DCD donors are not ultimately able to donate and this is a significant emotional and resource burden to families, healthcare workers and hospitals. A tool that allows accurate prediction of time to death following WLST (and thus the probability of successful donation) is urgently needed. Existing models have not been useful due to the lack of generalizability. Additionally, existing models have not included other important factors now recognized to be associated with time to death following WLST. The investigators will conduct a prospective, observational cohort study of all patients being considered for DCD in whom consent for donation is obtained to evaluate the association between neurologic and non-neurologic risk factors for apnea, other clinically important variables and time to death after WLST, and use these data to derive a generalizable predictive model for the prediction of the time to death following WLST in potential DCD donors.

NCT ID: NCT02318849 Completed - Clinical trials for Tissue and Organ Procurement

Online Intervention for ANHPI College Students

iDecide
Start date: November 1, 2014
Phase: N/A
Study type: Interventional

Taking advantage of college students' frequent use of online technology, including social networking sites (e.g., Instagram a social media site /Facebook a social networking site) and social media sites (e.g., YouTube), the investigators will create an online intervention that leverages this technology to engage and educate Asian, Native Hawaiian, Pacific Islanders (ANHPI)students about a range of topics related to organ donation following death.

NCT ID: NCT01922310 Completed - Clinical trials for Tissue and Organ Procurement

Communication Regarding Organ and Tissue Donation in Intensive Care

COMFORT
Start date: May 1, 2013
Phase: N/A
Study type: Interventional

The overarching aim of this study is to examine the process of organ donation decision-making and to determine whether changes in requesting practices change rates of consent for donation, and other family-based outcomes.

NCT ID: NCT01214018 Terminated - Clinical trials for Stress Disorders, Post-Traumatic

Evaluation of Post-traumatic Stress Among the Nearest Relatives of Brain-dead Organ Donors

Start date: May 15, 2011
Phase: N/A
Study type: Observational

The goal is to compare post tramautic stress between the nearest relatives of brain-dead patients who are organ donor to those of brain-dead patients who are not organ donors for medical, legal or opposition reasons.

NCT ID: NCT01213069 Completed - Clinical trials for Tissue and Organ Procurement

Staff Opinions and Knowledge Concerning Organ and Tissue Harvesting: an Investigation Among the Patient Care Personnel in the South-Mediterranean Region of France

Start date: March 2010
Phase: N/A
Study type: Observational

The goal of this study is to evaluate the knowledge of paramedical and medical care personnel concerning organ and tissue donations, as well as their opinions on this activity.