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Tinnitus Treatment With Piribedil Guided by Acoustic Otoemissions and Electrocochleography — piribedil  

Tinnitus Clinical Trial

Official title:
Tinnitus Treatment With Piribedil Guided by Acoustic Otoemissions and Electrocochleography

Clinical Trial Summary

Tinnitus is defined as the perception of sound in the absence of a external source. About 15 % of the population is believed to experience tinnitus and for about 20 % of them it may become a very serious problem. Total comprehension of tinnitus pathophysiology has not yet been achieved, but modern theories focus in brain hyperactivity following inner ear damage, with involvement of various neurotransmitters. Piribedil,a dopamin agonist, has been used to treat tinnitus, focusing in dopamine release, which is inhibitory. Electrophysiological methods,like acoustic otoemissions and electrocochleography may reveal the changes in peripherical and central auditory pathways and help to choose the specific patients who could benefit from piribedil treatment.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00591994
Study type Interventional
Source Faculdade de Medicina de Valenca
Contact
Status Completed
Phase N/A
Start date November 2006
View Details
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