Evaluation of Trichoscopy in the Diagnosis of Tinea Capitis

Tinea Capitis Clinical Trial

— ETDT  

Official title:

Evaluation of Trichoscopy in the Diagnosis of Tinea Capitis. Prospective, Multicenter Study (ETDT)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02550496
• Other study ID #: PI2014_843_0019
• Status: Completed
• Phase: N/A
• Start date: March 4, 2015
• Est. completion date: January 23, 2017

Study information

• Verified date: August 2018
• Source: Centre Hospitalier Universitaire, Amiens
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Waiting for a proof by mycological culture is usually necessary before starting a systemic antifungal therapy. It therefore seems to us interesting to evaluate the benefit of using dermoscopy in clinical diagnosis of Tinea Capitis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 104
• Est. completion date: January 23, 2017
• Est. primary completion date: January 23, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• All patients with clinically diagnosed tinea capitis

• Patient has signed informed consent

Exclusion Criteria:

• Patient with kerion or tinea favosa

• Antifungal treatment within 15 days prior to inclusion

Related Conditions & MeSH terms

• Tinea
• Tinea Capitis

Intervention

Device:
• Dermoscopy

Locations

Country	Name	City	State
France	CHU Amiens	Amiens	Picardie
France	CHU Caen	Caen
France	CHRU Lille	Lille
France	CHU Rouen	Rouen

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire, Amiens

Country where clinical trial is conducted

France, 

References & Publications (6)

Ekiz O, Sen BB, Rifaioglu EN, Balta I. Trichoscopy in paediatric patients with tinea capitis: a useful method to differentiate from alopecia areata. J Eur Acad Dermatol Venereol. 2014 Sep;28(9):1255-8. doi: 10.1111/jdv.12246. Epub 2013 Aug 24. — View Citation

Hughes R, Chiaverini C, Bahadoran P, Lacour JP. Corkscrew hair: a new dermoscopic sign for diagnosis of tinea capitis in black children. Arch Dermatol. 2011 Mar;147(3):355-6. doi: 10.1001/archdermatol.2011.31. — View Citation

Micali G, Lacarrubba F, Massimino D, Schwartz RA. Dermatoscopy: alternative uses in daily clinical practice. J Am Acad Dermatol. 2011 Jun;64(6):1135-46. doi: 10.1016/j.jaad.2010.03.010. Epub 2011 Feb 3. Review. — View Citation

Sandoval AB, Ortiz JA, Rodríguez JM, Vargas AG, Quintero DG. [Dermoscopic pattern in tinea capitis]. Rev Iberoam Micol. 2010 Sep 30;27(3):151-2. doi: 10.1016/j.riam.2010.02.003. Epub 2010 Mar 24. Spanish. — View Citation

Slowinska M, Rudnicka L, Schwartz RA, Kowalska-Oledzka E, Rakowska A, Sicinska J, Lukomska M, Olszewska M, Szymanska E. Comma hairs: a dermatoscopic marker for tinea capitis: a rapid diagnostic method. J Am Acad Dermatol. 2008 Nov;59(5 Suppl):S77-9. doi: — View Citation

Zalaudek I, Argenziano G, Di Stefani A, Ferrara G, Marghoob AA, Hofmann-Wellenhof R, Soyer HP, Braun R, Kerl H. Dermoscopy in general dermatology. Dermatology. 2006;212(1):7-18. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The presence of several hair with at least one dermoscopic appearance specific of tinea capitis	The presence of several hair with at least one dermoscopic appearance Specific of tinea capitis ( corkscrew hair , comma hairs, interrupted (Morse code-like) hairs, hair shafts covered by whitish sheaths, zig-zag shaped hairs) correlating with The growth of a dermatophyte in the fungal culture.	baseline
Secondary	Dermoscopic appearance (corkscrew hair, comma hairs, interrupted (Morse code-like) hairs, hair shafts covered by whitish sheaths, zig-zag shaped hairs) according to microscopic pathogenic species.		baseline
Secondary	Concordance of dermoscopic appearance for each of the two operators.	Concordance between dermoscopic interpretation (corkscrew hair, comma hairs, interrupted (Morse code-like) hairs, hair shafts covered by whitish sheaths, zig-zag shaped hairs) of the dermatologist during the initial consultation and dermoscopic interpretation on the photographs by a blinded trained practitioner.	baseline
Secondary	Presence of a green fluorescence or not under the light of a Wood's lamp by comparing it with the result of the fungal culture.		baseline
Secondary	Introduction or not of a local or general presumptive treatment by the clinician while waiting for the result of the fungal culture.		baseline