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Time Restricted Feeding clinical trials

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NCT ID: NCT05740254 Recruiting - Pediatric Obesity Clinical Trials

Early vs. Late Time Restricted Eating in Adolescents With Obesity at Risk for Diabetes

Start date: March 27, 2023
Phase: N/A
Study type: Interventional

Many adolescents find it challenging to adhere to conventional treatment for pediatric obesity because they require daily calorie counting, easy access to fresh food, and the ability to change the home environment. As such, adherence is poor which limits efficacy. One simpler and promising approach is limiting the timing of eating, instead of changing the food quality or quantity. This approach is called, Time-restricted eating (TRE) and involves eating over an 8- to 10-hour eating window and fasting for the remainder of the day.

NCT ID: NCT05732935 Recruiting - Alzheimer Disease Clinical Trials

Fasting ENHANCE Pilot Study

Start date: March 13, 2023
Phase: N/A
Study type: Interventional

Grounded in the principles of geroscience, the proposed Fasting ENHANCE study will test whether a time restricted eating (TRE) regimen can improve cognitive function and other aspects of successful aging in a safe and sustainable manner in at risk overweight older adults. Specifically, this study will evaluate whether TRE can improve cognitive and physical function, as well as self-reported sleep, mood, and quality of life, in overweight, older adults (age > 65 years) who are at high risk of cognitive decline due to self-reported cognitive difficulties. Eligible participants will be assigned to either a TRE intervention, in which they will be instructed to fast for a target of 16 hours per day, or a successful aging (SA) comparison group for a 24-week period.

NCT ID: NCT05730231 Active, not recruiting - Hypertension Clinical Trials

Clinical Trials of Effects of Time Restricted Eating on Health Parameters in Adults

TRE
Start date: March 3, 2023
Phase: N/A
Study type: Interventional

In a randomized controlled trial we will research the effect of calorie restriction with early and mid-day time-restricted eating (TRE) and daily calorie restriction on weight loss and human health parameters. Participants will be divided into three groups: early time-restriction group (8:00 AM to 4:00 PM), mid-day restriction group (1:00 PM to 9:00 PM) and daily calorie restriction group (8:00 AM to 9:00 PM). Participants will follow dietary strategy with three planned meals and calorie restriction. Anthropometrical and biochemical parameters will be measured at baseline, after one month, two months and at after three months of intervention. Resting metabolic rate, ultrasound scan of abdomen and ultrasound scan of carotid arteries will be measured at baseline and after three months of intervention. In addition, stool samples will be also taken at baseline and after three months of intervention.

NCT ID: NCT05639244 Completed - Clinical trials for Myocardial Infarction

Time Restricted Eating and Innate Immunity

SIGNATURE
Start date: November 17, 2022
Phase: N/A
Study type: Interventional

The goal of this cross over study is to investigate the effect of short term time restricted eating (TRE) on the innate immune system in patients with a history of myocardial infarction.

NCT ID: NCT05628012 Recruiting - Weight Loss Clinical Trials

Circadian Time Restricted Eating

CTRE
Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to learn more about how the time in which participants consume their meals relative to their personalized circadian rhythm influences their overall cardiometabolic health and weight. The investigators are hoping to discover if a circadian-based time restricted eating intervention will improve cardiometabolic health and decrease weight. The protocol is a 46 day prospective cohort study that includes both field and in-laboratory data collection in overweight and obese individuals.

NCT ID: NCT05579158 Completed - Clinical trials for Non-Alcoholic Fatty Liver Disease

Effects of Time-restricted Eating Supported by Mobile Technology in Patients With Non-alcoholic Fatty Liver Disease: Randomized Controlled Trial

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

In non-alcoholic fatty liver disease (NAFLD), it is established that calorie restriction is the most essential dietary modification. The time-restricted diet is successful lowering total calorie consumption and insulin resistance, and is anticipated to be beneficial for patients with NAFLD. Therefore, this study aims to conduct a prospective study to determine the effect of time-restricted diet via a mobile application on the amount of intrahepatic fat and 10-year cardiovascular disease risk in patients with NAFLD.

NCT ID: NCT05558423 Recruiting - Clinical trials for Intermittent Fasting

ZOE Health Study: The Intermittent Fasting Study

Start date: October 24, 2022
Phase: N/A
Study type: Interventional

The timing of food intake (chrononutrition) is emerging as a key regulator of circadian rhythm in metabolic organs. A wealth of research has been conducted on intermittent fasting, and time restricted eating (TRE) specifically, investigating the temporal patterns of diet (eating window, time of eating, time of largest energy intake) and their impact on disease risk, with overall beneficial impact on health. Studies have been conducted in a parallel or single arm design, while cross-over and the efficacy of TRE in ameliorating appetite and symptom burden within an individual remains unclear.

NCT ID: NCT05548517 Recruiting - Weight Loss Clinical Trials

TRE: Microbiome, Metabolic Health and Bone

TREMBO
Start date: October 15, 2022
Phase: N/A
Study type: Interventional

In the Time-Restricted Eating: Microbiome and Bone (TREMBO) study, the primary goal is to determine the effect of time-restricted eating with caloric restriction compared to caloric restriction alone on body weight, the gut microbiota, and bone health in older women who are overweight or obese.

NCT ID: NCT05420181 Recruiting - Clinical trials for Time Restricted Feeding

Prolonged Overnight Fast on Energy Metabolism and Skeletal Muscle Protein Synthesis in Humans

Start date: May 30, 2019
Phase: N/A
Study type: Interventional

Recent research shows that timing of nutritional intake and daily periods of fasting may have important health effects. In humans, limiting daily food intake to a narrow window (typically ~8 hours) can bring about some beneficial changes in blood concentrations of fats, sugar and the hormone insulin. It is thought that many of these changes are due to the prolonged daily fasting periods and humans will have regularly experienced prolonged fasting periods throughout evolution. In the modern era, food access is widely available and it is not uncommon for the time between breakfast and a late night snack to exceed 14 hours. We have recently shown that extending habitual daily periods of fasting to 16 hours per day also improves the ability of skeletal muscle to take up amino acids, the building blocks of protein. We are interested in studying whether a single episode of prolonged overnight fast (~16 hours), when compared to a normal overnight fast of 10 hours, is sufficient to stimulate skeletal muscle protein synthesis in response to dietary protein ingestion in healthy humans.

NCT ID: NCT05365529 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Time-Restricted Eating for Type II Diabetes: TRE-T2D

TRE-T2D
Start date: May 16, 2022
Phase: N/A
Study type: Interventional

This is a randomized clinical trial to assess the feasibility and efficacy of time-restricted eating (TRE) to improve glucose regulation and cardiovascular health of participants with type 2 diabetes mellitus (T2DM). Participants will be randomized into 2 groups: 1) standard of care (SOC), in which they will continue to follow their physician's treatment plan, or 2) SOC and TRE (8-10 hours eating window).