Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics

Status Completed

Clinical Trial Summary

The study will examine whether combining Comprehensive Behavioral Intervention for Tics (CBIT) with inhibition of the supplementary motor area (SMA) using transcranial magnetic stimulation (TMS) normalizes activity in the SMA-connected circuits, improves tic suppression ability, and enhances CBIT outcomes in young people with tic disorder. The study will also examine different TMS dosing strategies.

Clinical Trial Description

All participants will receive 10 daily sessions of CBIT, a well-established behavioral treatment that is considered by the American Academy of Neurology to be the first-line intervention for tics. Immediately prior to each CBIT session, participants will undergo TMS targeting the SMA. The specific type of TMS procedure will be randomly assigned between subjects and be either: 1 Hz repetitive TMS (rTMS), continuous theta burst stimulation (cTBS), or sham stimulation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04578912
Study type	Interventional
Source	University of Minnesota
Contact
Status	Completed
Phase	N/A
Start date	November 1, 2020
Completion date	December 31, 2023

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