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Clinical Trial Summary

The investigation of thyroid nodules is limited by the fact that up to 49% of the fine needle aspirations (FNA) performed are of "indeterminate cytological signification". Moreover, no fully reliable molecular marker for thyroid cancer have been described. The goal of this project is to study the expression of a specific kind of protein convertase in benign and in malignant thyroid nodules to determine its potential as a biomarker.


Clinical Trial Description

Patients that underwent thyroidectomy at the CIUSSS de l'Estrie-CHUS will be recruited and classified according to the pathological diagnosis. An immunohistochemistry technique, developed and calibrated for the specific protein convertase studied, will be undertaken. Results will be interpreted by a specialized pathologist. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03160482
Study type Observational
Source Université de Sherbrooke
Contact
Status Completed
Phase
Start date May 15, 2017
Completion date January 15, 2018

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