The Role of Elastography in the Diagnosis of Thyroid Nodules

Status Completed

Clinical Trial Summary

The primary objective of this study is to evaluate the role of elastography (along with echographic and cytological data) as a diagnostic tool for thyroid cancer

Clinical Trial Description

Ultrasound is considered the first line examination in the exploration of the thyroid nodule. Echotexture analysis often identifies nodules at risk of malignancy, but does not replace or exclude an additional cytological exploration. Cytology, although effective, also has limitations, particularly when samples are vesicular and it is difficult discern between a benign or malignant state. The creation of a noninvasive method in this context could help to avoid invasive tests or "useless" surgical procedures.

Ultrasound elastography, which assesses tissue deformability, may provide valuable information concerning benign soft tissue characteristics, whereas malignant lesions are harder in consistency. Interest in this method, already proposed for other organs, has recently increased due to the emergence of specifically created software that enables objective evaluation of the hardness of the nodule during a conventional ultrasound analysis. The main hypothesis of this study is that elastography should allow better selection of candidates for thyroid surgery. ;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01292044
Study type	Interventional
Source	Centre Hospitalier Universitaire de Nimes
Contact
Status	Completed
Phase	N/A
Start date	November 2011
Completion date	August 2014

View Details

See also
Status	Clinical Trial	Phase
Terminated	`NCT04614389` - Utility of Contrast-Enhanced Sonography and Shear Wave Elastography	N/A
Recruiting	`NCT03295955` - Comparing Efficacy of Postoperative Oral Antibiotic Use in Trans-Oral Thyroidectomy	N/A
Completed	`NCT04647006` - Comparison of TOETVA and Conventional Thyroidectomy	N/A
Not yet recruiting	`NCT06029946` - B-mode Ultrasound, Sono-Elastography, and Diffusion-weighted Imaging MRI in Thyroid Nodules
Recruiting	`NCT05025046` - NGS-based Thyroscan Genomic Classifier in the Diagnosis of Thyroid Nodules
Terminated	`NCT01320813` - Trial Comparing Complication Rates Associated With Robot-assisted Thyroidectomy to External Thyroidectomy	N/A
Completed	`NCT00877630` - Minimal Invasiveness of Endoscopic Thyroidectomy	N/A
Completed	`NCT01964508` - microRNA in Thyroid Cancer
Completed	`NCT06306599` - Ultrasound Operator Influence on Diagnostics With AI for Thyroid Nodules - Clinial Trial	N/A
Recruiting	`NCT04730726` - In Vivo Multispectral Optoacoustic Imaging of Thyroid Nodules	N/A
Not yet recruiting	`NCT03884140` - Clinical Diagnostic Approach for Cases of Thyroid Nodules
Completed	`NCT04277455` - Effect of Ultrasound Guided Laser Ablation Therapy on Symptomatic Benign Thyroid Nodules	N/A
Recruiting	`NCT02225509` - Clinical Validation of a Molecular Signature to Detect Cancer in Thyroid Nodules With Indeterminate Cytology	N/A
Completed	`NCT00552253` - Levothyroxine Treatment in Thyroid Benign Nodular Goiter	N/A
Not yet recruiting	`NCT03700762` - Application of Ultrasonic Gray-scale Ratio in Differentiating Benign From Malignant Thyroid Nodules.
Enrolling by invitation	`NCT01757834` - Shear Wave Ultrasound Elastography in Noninvasive Diagnosis of Thyroid Nodules	N/A
Completed	`NCT00858104` - Percutaneous Laser Ablation in Benign Thyroid Nodules.Long Term Results	Phase 4
Completed	`NCT00651625` - Reciprocating Medical Devices - a Study of a New Safety Device	N/A
Completed	`NCT05132478` - The Effect of Surgeon Emotional Support on Treatment Choice for Low-risk Thyroid Cancer	N/A
Withdrawn	`NCT03395925` - Evaluation of the Thyroid Volume After Radiofrequency Ablation of Thyroid Nodules and Recurrent Thyroid	N/A