Feasibility of Neostigmine for Intraoperative Neuromonitoring in Thyroid

Status Completed

Clinical Trial Summary

Clinical Trial Description

For successful intraoperative neuromonitoring (IONM), adequate reversal of neuromuscular blocking agent is a prerequisite in thyroid surgery with . The aim of this study is to investigate the feasibility of neostigmine just after tracheal intubation on the IONM in thyroid surgery. This study will be performed as a randomized controlled trial with two groups (N group: neostigmine group and NS group: normal saline group). For the N group, neostigmine (0.03 mcg / kg) and glycopyrrolate with a 5:1 ratio will be administered just after tracheal intubation. For the NS group, normal saline with a same volume of the N group will be administered just after tracheal intubation. For all patients of two groups, investigators evaluate the quality of signal of IONM during the surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04873531
Study type	Interventional
Source	Seoul National University Hospital
Contact
Status	Completed
Phase	N/A
Start date	May 10, 2021
Completion date	August 31, 2021

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Feasibility of Neostigmine for Intraoperative Neuromonitoring in Thyroid Surgery

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms