Anxiety & Depression in Thyroid Cancer Patients

Thyroid Cancer Clinical Trial

Official title:

Anxiety, Depression and Quality of Life in Thyroid Cancer Patients

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06269731
• Other study ID #: Thyroid cancer
• Status: Not yet recruiting
• Start date: March 2024
• Est. completion date: March 2026

Study information

• Verified date: February 2024
• Source: Assiut University
• Contact: salma mamdouh
• Phone: +201016297915
• Email: salmamamdouhmm[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

1. To identify the prevalence of both anxiety and depression in thyroid cancer patients

2. To assess quality of life in thyroid cancer patients

Description:

In recent years, increasing attention has been paid to mental health among cancer patients.

Thyroid cancer is one of the most frequent endocrine neoplasia. It consists of 4 subtypes of papillary thyroid cancer, follicular thyroid cancer, medullary thyroid cancer, and anaplastic thyroid cancer.

Which is usually asymptomatic in the early stages, but symptoms such as neck pain, hoarseness, and dysphagia may occur as the disease progresses. TC is diagnosed by physical examination, analysis of thyroid hormone levels, imaging, and biopsy.

Anxiety and depression are the most common psychological problems in the treatment of cancer patients and are related to the majority of medical diseases and physical symptoms.

Studies have suggested that anxiety and depression are common in patients with thyroid cancer.

Therefore, quality of life which includes psychological, social, and spiritual well-being, has become an important consideration .

These findings highlight the importance of identifying thyroid cancer patients needs to allow better and more adequate care and support.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 159
• Est. completion date: March 2026
• Est. primary completion date: December 2025
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

1. Age at or more than 18 years old

2. None of the patients had history of other psychiatric illness

3. Both sex

4. Accept to participate in the study

Exclusion Criteria:

1. Age less than 18 years old

2. Previous history of other psychiatric illness

3. substance abuser or dependence

4. Refuse to participate in the study

Related Conditions & MeSH terms

• Depression
• Thyroid Cancer
• Thyroid Diseases
• Thyroid Neoplasms

Intervention

Behavioral:
• Hamilton depression Rating Scale
also known as the Ham-D is the most widely used clinician-administered depression assessment scale. The original version contains 17 items (HDRS17) pertaining to symptoms of depression experienced over the past week. Although the scale was designed for completion after an unstructured clinical interview, The scale has been translated into a number of languages including French, German, Italian, Thai , Turkish and Arabic version by Mostafa Lotfy.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (3)

Alexander K, Lee SC, Georgiades S, Constantinou C. The "not so good" thyroid cancer: a scoping review on risk factors associated with anxiety, depression and quality of life. J Med Life. 2023 Mar;16(3):348-371. doi: 10.25122/jml-2022-0204. — View Citation

Dionisi-Vici M, Fantoni M, Botto R, Nervo A, Felicetti F, Rossetto R, Gallo M, Arvat E, Torta R, Leombruni P. Distress, anxiety, depression and unmet needs in thyroid cancer survivors: a longitudinal study. Endocrine. 2021 Dec;74(3):603-610. doi: 10.1007/s12020-021-02786-y. Epub 2021 Jun 18. — View Citation

Tagay S, Herpertz S, Langkafel M, Erim Y, Bockisch A, Senf W, Gorges R. Health-related Quality of Life, depression and anxiety in thyroid cancer patients. Qual Life Res. 2006 May;15(4):695-703. doi: 10.1007/s11136-005-3689-7. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the prevalence of anxiety in thyroid cancer patients	To identify the prevalence of anxiety in thyroid cancer patients by using Hamilton Anxiety Rating Scale	baseline
Primary	the prevalence of depression in thyroid cancer patients	To identify the prevalence of depression in thyroid cancer patients by using Hamilton Depression Rating Scale	baseline
Secondary	assess quality of life in thyroid cancer patients	Detect quality of life in patients with thyroid cancer by using Short form 36 Quality of life questionnaire	baseline