Clinical Trials Logo

Clinical Trial Summary

Hyperthermic intrathoracic chemotherapy (HITOC) offers an additional treatment option for malignant pleural tumors after surgical cytoreduction. Especially it is used to further improve local tumor control in thymic malignancies with pleural spread, who underwent multimodality therapy including surgical resection. A phase II clinical study was conducted to explore the efficacy and safety of surgery followed by HITOC (POD1: DOX, POD2: cisplatin) for thymic epithelial tumors with pleural spread or recurrence.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05446935
Study type Interventional
Source Shanghai Zhongshan Hospital
Contact Jianyong Ding, MD
Phone 18616881268
Email ding.jianyong@zs-hospital.sh.cn
Status Recruiting
Phase N/A
Start date October 1, 2022
Completion date November 30, 2025

See also
  Status Clinical Trial Phase
Not yet recruiting NCT06200233 - Rivoceranib in Patients With Metastatic Thymic Epithelial Tumor Phase 2
Not yet recruiting NCT03212027 - Preoperative Prediction of of Thymic Epithelial Tumors by Diffusion-Weighted MR Imaging N/A
Recruiting NCT04667793 - Clinical Study of Neoadjuvant PD-1 Antibody (Toripalimab) Plus Chemotherapy for Locally Advanced Thymic Epithelial Tumor Phase 2
Recruiting NCT02724696 - French National Observatory of Patients With Thymic Epithelial Tumor
Recruiting NCT05667948 - Molecular Analysis and Treatment Options of Thymic Malignancies
Recruiting NCT04522687 - Influence of Radiotherapy and Chemotherapy in the Value of Peripheral Blood Lymphocyte Subsets Among Thoracic Cancer
Recruiting NCT04417660 - Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma Phase 2
Not yet recruiting NCT04517539 - Abscopal Effect of SBRT in Combination With rhGM-CSF and INF-α 2b for Metastatic Thymic Epithelial Tumors Phase 2
Recruiting NCT06301945 - Artificial Intelligence Prediction Tool in Thymic Epithelial Tumors
Recruiting NCT05104736 - PT-112 in Subjects With Thymoma and Thymic Carcinoma Phase 2
Recruiting NCT03858582 - neoadjuvant_thymic Epithelial Tumor Phase 2
Recruiting NCT06311955 - Clinical Study of Postoperative Carbon Ion Radiotherapy for Thymus Tumor With Residual Tumor Phase 2