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Thrombosis clinical trials

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NCT ID: NCT05923658 Not yet recruiting - Thrombosis Clinical Trials

How Clinicians Manage Their Patients Who May Need Antithrombotic Care

Start date: October 1, 2023
Phase:
Study type: Observational

This study aims to assess the knowledge and provide an opportunity for education to clinician attendees of the Canadian Cardiovascular Congress (CCC) meeting using a series of simulated patient case scenarios.

NCT ID: NCT05907486 Not yet recruiting - Thrombotic Disorder Clinical Trials

The Use of N-acetylcysteine for Thrombotic Events After Allogenic Hematopoietic Stem Cell Transplantation

Start date: August 1, 2023
Phase: Phase 3
Study type: Interventional

We aim to assess the the efficiency and safety of N-acetylcysteine for prevention of thrombotic events after allogenic hematopoietic stem cell transplantation.

NCT ID: NCT05900622 Not yet recruiting - Clinical trials for Deep Vein Thrombosis

A Study of Modified Limb Braking and Early Bed Mobility Strategies After Femoral Venipuncture Intervention

Start date: July 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare in describe participant population health conditions. The main questions it aims to answer are: - To obtain the limb movement and bed mobility limits after femoral venipuncture, in order to provide a basis and support for clinical reduction of postoperative braking time and alleviation of postoperative patient subjective discomfort - To analyze the effect of perioperative factors such as anticoagulation and sheath size on the complication rate, so as to develop a detailed and systematic strategy to stop bleeding after femoral venipuncture - The advantages and necessity of reducing the postoperative braking time in bed were demonstrated by objective evaluation of patients' postoperative subjective feelings and mental status. In this prospective study, 150 patients who underwent femoral vein puncture intervention were selected by inclusion and exclusion criteria, and were randomly divided into control group, trial A group and trial B group by SPSS software, with 50 cases each. In the control group, the lower limb of the punctured side was braked for 4 hours + 8 hours after routine postoperative activities; in the trial A group, the lower limb of the punctured side was braked for 2 hours + 4 hours after postoperative activities; in the trial B group, the lower limb of the punctured side was braked for no postoperative activities + 2 hours after postoperative activities, and the corresponding evaluation indexes and questionnaires were used to record the hemostasis at the puncture site, whether complications occurred and the subjective feelings of patients in each group after completing the corresponding strategies. The data were also recorded along with the general information of the patients and the factors that may cause bleeding in the perioperative period. Statistical analysis was used to classify, summarize and draw conclusions about the data obtained, analyze the limit of braking bed time, and formulate scientific hemostatic strategies.

NCT ID: NCT05889897 Not yet recruiting - Vascular Thrombosis Clinical Trials

Prevalence, Risk Factors and Outcomes of Pediatric Vascular Thrombosis

Start date: August 1, 2023
Phase:
Study type: Observational

This study is aimed to identify the prevalence, risk factors and outcomes of children with either venous or arterial thromboembolism admitted to children hospital Assiut University aiming at early detection and avoidance of catastrophic complications .

NCT ID: NCT05882370 Not yet recruiting - Clinical trials for Hepatocellular Carcinoma

TIPS Plus Cadonilimab in Advanced HCC With Tumor Thrombosis-associated Portal Hypertension:a Prospective, Single-arm, Phase II Study

Start date: July 1, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of transjugular intrahepatic portosystemic shunt (TIPS) plus Cadonilimab (a PD-1/CTLA-4 bispecific antibody) in advanced hepatocellular carcinoma (BCLC-C Stage) accompanied by tumor thrombosis-associated portal hypertension.

NCT ID: NCT05881798 Not yet recruiting - Pulmonary Embolism Clinical Trials

Post-Market Celect Platinum Vena Cava Filter and Gunther Tulip Retrieval Set Study

Start date: June 2024
Phase:
Study type: Observational [Patient Registry]

This prospective, observational, post-market study will be performed to collect patient-level data on the Celect Platinum Vena Cava Filter Sets and the Günther Tulip Vena Cava Filter Retrieval Set to confirm continued safety and performance of the devices throughout their expected lifetime and continued acceptability of the benefit:risk ratio. Additionally, the study intends to evaluate longer-term (i.e., up to 5 years) outcome data while the filter is indwelling.

NCT ID: NCT05872841 Not yet recruiting - Clinical trials for Portal Vein Thrombosis

H101 Combined With TACE for Primary Hepatocellular Carcinoma With Portal Vein Thrombosis

Start date: June 1, 2023
Phase: Phase 2
Study type: Interventional

This study is the first to compare the efficacy and safety of recombinant human adenovirus type 5 injection via hepatic artery infusion combined with TACE-based combination therapy for the treatment of patients with stage IIIa primary hepatocellular carcinoma with portal vein carcinoma thrombosis, providing a safe and reliable treatment method for the clinical treatment of this group of patients, and also providing a reference and basis for the treatment of other tumors with this new treatment model.

NCT ID: NCT05840744 Not yet recruiting - Clinical trials for Thrombosis in Children

Evaluation of Risk Factors and Outcome of Thrombosis in Children

Start date: May 1, 2023
Phase:
Study type: Observational

Pediatric thrombosis is multifactorial, and usually risk factors either congenital or acquired are present. Patient may has one risk factor or more such as sepsis, cancers, congenital heart disease, post surgery , central venous catheter insertion, nephrotic syndrome, systemic lupus erythromatosis and inflammatory bowel disease. If there's no obvious risk factor for thrombosis, hereditary thrombophilia is suspected which results when an inherited factor, such as antithrombin , protein C or protein S deficiency.

NCT ID: NCT05830916 Not yet recruiting - Thrombosis Clinical Trials

Diagnostic Role of Antiphospholipid Antibodies and Microparticles in Immune Thrombocytopenic Patients With Thrombosis

Start date: September 2024
Phase:
Study type: Observational

Identify the procoagulant profile in immune thrombocytopenic patients with thrombosis. Clinical implications of antiphospholipid antibodies in ITP patients with thrombosis. Diagnostic role of microparticles in ITP patients with thrombosis.

NCT ID: NCT05793671 Not yet recruiting - STEMI Clinical Trials

Follow up of Clinical Outcome of Deferred vs Immediate Stenting in High Thrombus Stemi Patients

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

To compare the effect of immediate stenting versus deferred stenting - with use of glycoproteinIIbIIIa inhibitor & low molecular weight heparin - on the clinical outcome -3 and 6 months after stenting & also infarct size using troponin level during hospital stay . Clinical outcome - 3 and 6 months - after stenting which includes re-infarction, repeat percutaneous coronary intervention, coronary artery bypass grafting , Congestive heart failure, cardiac death & cerebrovascular accidents.