The Effect of Dexmedetomidine on Postoperative Quality of Recovery Clinical Trial
Official title:
The Effect of Preoperative Intravenous Dexmedetomidine on Postoperative Quality of Recovery: Randomized Study
Dexmedetomidine is a selective a2-agonist and a sedative with anti-inflammatory,analgesic,
and antiemetic effects, and its use for procedural sedation during endoscopy or ablation for
atrial fibrillation has been increasing. It is also used for sedation in the intensive care
unit. Recently, it was reported that dexmedetomidine is often used as an adjuvant for general
anesthesia. Sympatholysis of dexmedetomidine can attenuate the increased sympathetic tone
after surgery and result in antistress effects. In addition, opioid-sparing and analgesic
effects are promoted by the perioperative administration of dexmedetomidine. Although it has
been reported that the perioperative administration of dexmedetomidine improves quality of
recovery after spinal and ENT surgeries, the outcomes for patients who undergo laparoscopic
cholecystectomy remain poorly investigated.
The aims of this study were to evaluate the effects of preoperative dexmedetomidine
administration on quality of recovery by using the QoR-40 questionnaire in patients who
undergo laparoscopic cholecystectomy.
n/a